Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ASPH | Q12797 | 1/20 | 0.44 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | ALB | P02768 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.36 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | RARB | P10826 | 2/20 | 0.36 |
| ▸ | RARA | P10276 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5872835 | 0.88 | KDM4E (0.52) | KDM4EASPHKDM8KEAP1NFE2L2 | |
| SCHEMBL31336112 | 0.85 | CSNK2A1 (0.42) | KDM4ESMN1; SMN2ALBMAOBCA12 | |
| SCHEMBL9053212 | 0.84 | KEAP1 (0.43) | KDM4EASPHKDM8SMN1; SMN2KEAP1 | |
| SCHEMBL30753199 | 0.83 | TSHR (0.43) | SMN1; SMN2MAOBCA1CA2CA4 | |
| SCHEMBL13390 | 0.83 | TSHR (0.43) | SMN1; SMN2MAOBCA1CA2CA4 | |
| SCHEMBL6561685 | 0.83 | TSHR (0.46) | KDM4ESMN1; SMN2KEAP1NFE2L2MAOB | |
| SCHEMBL26292285 | 0.83 | TBK1 (0.45) | KDM4EASPHKDM8KEAP1NFE2L2 | |
| SCHEMBL363928 | 0.80 | KEAP1 (0.50) | KDM4EASPHKDM8KEAP1NFE2L2 | |
| SCHEMBL31258575 | 0.80 | KEAP1 (0.50) | KDM4EASPHKDM8KEAP1NFE2L2 | |
| SCHEMBL9038615 | 0.80 | ALDH1A1 (0.43) | KDM4ESMN1; SMN2MAOBCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-8259521-A | — | — | None | — | — | JP | disclosed |
| JP-H08259521-A | SUBSTITUTED BENZOYL CHLORIDE DERIVATIVE AND ITS PRODUCTION | CENTRAL GLASS CO LTD | 1996-10-08 | — | — | JP | disclosed |