Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 4/20 | 0.74 |
| ▸ | HTR2A | P28223 | 8/20 | 0.64 |
| ▸ | HTR2C | P28335 | 5/20 | 0.63 |
| ▸ | HTR2B | P41595 | 5/20 | 0.63 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.54 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | HTR1A | P08908 | 3/20 | 0.50 |
| ▸ | DRD3 | P35462 | 4/20 | 0.46 |
| ▸ | DRD1 | P21728 | 1/20 | 0.46 |
| ▸ | HTR1D | P28221 | 1/20 | 0.46 |
| ▸ | HTR1B | P28222 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29445150 | 1.00 | HTR6 (0.74) | HTR6HTR2AHTR2CHTR2BMTNR1A | |
| SCHEMBL29758535 | 0.85 | HTR6 (1.00) | HTR6HTR2AHTR2CHTR2BMTNR1A | |
| SCHEMBL19235737 | 0.85 | HTR6 (1.00) | HTR6HTR2AHTR2CHTR2BMTNR1A | |
| SCHEMBL29993252 | 0.85 | HTR6 (1.00) | HTR6HTR2AHTR2CHTR2BMTNR1A | |
| Hydrochloric Acid SCHEMBL4208783 | 0.84 | HTR6 (0.97) | HTR6HTR2AHTR2CHTR2BMTNR1A | |
| SCHEMBL29992863 | 0.82 | HTR6 (0.75) | HTR6HTR2AHTR2CHTR2BMTNR1A | |
| SCHEMBL8800092 | 0.82 | HTR2A (0.57) | HTR6HTR2AHTR2CHTR2BMTNR1A | |
| SCHEMBL16437208 | 0.82 | HTR2A (0.69) | HTR6HTR2AHTR2CHTR2BMTNR1A | |
| SCHEMBL15678352 | 0.81 | HTR2A (0.56) | HTR6HTR2AHTR2CHTR2BKDM4E | |
| SCHEMBL16612881 | 0.81 | HTR2A (0.68) | HTR6HTR2AHTR2CHTR2BMTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240067639-A1 | SMALL MOLECULES THAT TARGET THE RNA THAT CAUSES ALS | University of Florida Research Foundation, Incorporation (US) | 2024-02-29 | — | — | US | disclosed |
| US-20240067639-A1 | SMALL MOLECULES THAT TARGET THE RNA THAT CAUSES ALS | University of Florida Research Foundation, Incorporation (US) | 2024-02-29 | — | — | US | disclosed |
| WO-2022055922-A1 | SMALL MOLECULES THAT TARGET THE RNA THAT CAUSES ALS | EXPANSION THERAPEUTICS, INC. (US) | 2022-03-17 | — | — | WO | disclosed |
| US-8945397-B2 | Methods of inhibiting cyanobacteria growth by administering gramine derivatives | CYANOTROL, LLC (US) | 2015-02-03 | — | — | US | disclosed |
| US-8945397-B2 | Methods of inhibiting cyanobacteria growth by administering gramine derivatives | CYANOTROL, LLC (US) | 2015-02-03 | — | — | US | disclosed |
| US-8945397-B2 | Methods of inhibiting cyanobacteria growth by administering gramine derivatives | CYANOTROL, LLC (US) | 2015-02-03 | — | — | US | disclosed |
| US-20140110350-A1 | METHODS OF INHIBITING CYANOBACTERIA GROWTH BY ADMINISTERING GRAMINE DERIVATIVES | SAN FRANCISCO STATE UNIVERSITY (US) | 2014-04-24 | — | — | US | disclosed |
| US-20140110350-A1 | METHODS OF INHIBITING CYANOBACTERIA GROWTH BY ADMINISTERING GRAMINE DERIVATIVES | SAN FRANCISCO STATE UNIVERSITY (US) | 2014-04-24 | — | — | US | disclosed |
| US-20140110350-A1 | METHODS OF INHIBITING CYANOBACTERIA GROWTH BY ADMINISTERING GRAMINE DERIVATIVES | SAN FRANCISCO STATE UNIVERSITY (US) | 2014-04-24 | — | — | US | disclosed |
| US-8642785-B2 | Photolabile dinitroindolinyl based compounds | PHILADELPHIA HEALTH & EDUCATION CORPORATION (US) | 2014-02-04 | — | — | US | disclosed |
| US-20100096252-A1 | PHOTOLABILE DINITROINDOLINYL BASED COMPOUNDS | PHILADELPHIA HEALTH & EDUCATION CORPORATION, D/B/A DREXEL UNIVERSITY COLLEGE OF (US) | 2010-04-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240067639-A1 | SMALL MOLECULES THAT TARGET THE RNA THAT CAUSES ALS | FUS, SNRPE, RRBP1 | HTR6 2485/4885HTR2A 3031/4885HTR2C 3069/4885 |
| US-20100096252-A1 | PHOTOLABILE DINITROINDOLINYL BASED COMPOUNDS | AANAT, TPH2, HTR3C | HTR6 22/4885HTR2A 41/4885HTR2C 7/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.