Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.49 |
| ▸ | RAB9A | P51151 | 6/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | MMP1 | P03956 | 3/20 | 0.44 |
| ▸ | MMP2 | P08253 | 3/20 | 0.44 |
| ▸ | MMP9 | P14780 | 3/20 | 0.44 |
| ▸ | MITF | O75030 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12509646 | 0.80 | NPC1 (0.76) | NPC1RAB9ATP53ALDH1A1PKM | |
| SCHEMBL12509568 | 0.79 | RAB9A (0.55) | NPC1RAB9ATP53ALDH1A1PKM | |
| SCHEMBL10055020 | 0.69 | NPC1 (0.94) | NPC1RAB9ATP53ALDH1A1PKM | |
| SCHEMBL13630703 | 0.68 | MEN1 (0.58) | NPC1RAB9ATP53ALDH1A1PKM | |
| SCHEMBL5534468 | 0.68 | HTR3E (0.58) | NPC1RAB9AALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL4893387 | 0.67 | TP53 (0.87) | NPC1RAB9ATP53ALDH1A1SMN1; SMN2 | |
| SCHEMBL31040569 | 0.67 | TP53 (0.87) | NPC1RAB9ATP53ALDH1A1SMN1; SMN2 | |
| SCHEMBL4256368 | 0.67 | NPC1 (1.00) | NPC1RAB9ATP53ALDH1A1PKM | |
| SCHEMBL2096261 | 0.65 | TP53 (0.68) | NPC1RAB9ATP53ALDH1A1PKM | |
| SCHEMBL2095227 | 0.65 | RAB9A (0.71) | NPC1RAB9ATP53ALDH1A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010034982-A1 | LIGANDS FOR AGGREGATED TAU MOLECULES | WISTA LABORATORIES LTD. (SG) | 2010-04-01 | — | — | WO | disclosed |