Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1G | O43497 | 3/20 | 0.43 |
| ▸ | CACNA1H | O95180 | 3/20 | 0.43 |
| ▸ | CACNA1I | Q9P0X4 | 3/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.37 |
| ▸ | SCD | O00767 | 7/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13393741 | 0.86 | SCD (0.49) | SCDALDH1A1 | |
| SCHEMBL12464531 | 0.76 | SCD (0.63) | SCD | |
| SCHEMBL14047539 | 0.68 | SCD (0.53) | CACNA1GCACNA1HCACNA1ISCDPOLB | |
| SCHEMBL14047625 | 0.68 | SCD (0.57) | CACNA1GCACNA1HCACNA1ISCDMEN1 | |
| SCHEMBL14047400 | 0.68 | SCD (0.57) | CACNA1GCACNA1HCACNA1ISCDMEN1 | |
| SCHEMBL14047581 | 0.68 | ALDH1A1 (0.45) | CACNA1GCACNA1HCACNA1ISCDPOLB | |
| SCHEMBL14047406 | 0.67 | SCD (0.44) | CACNA1GCACNA1HCACNA1IP2RX7SCD | |
| SCHEMBL13622275 | 0.65 | ATM (0.45) | POLBLMNA | |
| SCHEMBL14162398 | 0.65 | HTT (0.45) | POLBMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL14047595 | 0.65 | SCD (0.56) | CACNA1GCACNA1HCACNA1ISCDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010035052-A1 | TISSUE SELECTIVE STEAROYL-COA DESATURASE 1 INHIBITORS AND CELL BASED SCREENING ASSAY FOR THEIR IDENTIFICATION | GLENMARK PHARMACEUTICALS, S.A. (CH) | 2010-04-01 | — | — | WO | disclosed |