Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 3/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.34 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.33 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.32 |
| ▸ | TUBB | P07437 | 1/20 | 0.32 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.32 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.32 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.32 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.32 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.32 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.32 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.32 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13224765 | 0.86 | MAOB (0.45) | GPR52MAOBKDM4EALDH1A1LMNA | |
| SCHEMBL13394233 | 0.84 | GABRA1 (0.41) | ALOX5GABRA1GABRB2MAOBPDCD1 | |
| SCHEMBL18221375 | 0.81 | FFAR4 (0.35) | ALOX5GABRA1GABRB2GPR52CNR2 | |
| SCHEMBL15119647 | 0.79 | GABRA1 (0.47) | ALOX5GABRA1GABRB2MAOBPDCD1 | |
| SCHEMBL13394232 | 0.78 | ALDH1A1 (0.46) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL13025705 | 0.77 | FFAR4 (0.32) | ALOX5GABRA1GABRB2GPR52CNR2 | |
| SCHEMBL15119653 | 0.77 | HSD11B1 (0.41) | ALOX5GABRA1GABRB2CNR2 | |
| SCHEMBL10009929 | 0.76 | HRH3 (0.43) | GPR52MAOB | |
| SCHEMBL12834690 | 0.76 | CYP17A1 (0.33) | ALOX5GABRA1GABRB2GPR52CNR2 | |
| SCHEMBL18902086 | 0.76 | MAOB (0.58) | GPR52MAOBTUBB4ATUBBTUBA3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8361568-B2 | Liquid-crystalline medium | MERCK PATENT GMBH (DE) | 2013-01-29 | — | — | US | disclosed |
| US-20100102275-A1 | LIQUID-CRYSTALLINE MEDIUM | KLASEN-MEMMER MELANIE | 2010-04-29 | — | — | US | disclosed |