SCHEMBL133943

SCHEMBL133943

CC(O)COC(C)COCCC[Si](C)(C)O[Si](C)(C)O[Si](C)(CCC(F)(F)F)O[Si](C)(C)O[Si](C)(C)CCCOCC(C)OCC(C)O

nearest known ligand 0.40

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10198658 0.96 TDP1 (0.37) TDP1
SCHEMBL25698473 0.95 TDP1 (0.36) TDP1
SCHEMBL12376990 0.94 TDP1 (0.40) TDP1
SCHEMBL133940 0.93 TDP1 (0.35) TDP1
SCHEMBL18199245 0.93 TDP1 (0.35) TDP1
SCHEMBL133991 0.92 HSD17B10 (0.33)
SCHEMBL25698479 0.89 TDP1 (0.39) TDP1
SCHEMBL133719 0.86 TDP1 (0.53) TDP1
SCHEMBL133724 0.85 HSD17B10 (0.36)
SCHEMBL12588651 0.82 HSD17B10 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11678968-B2 Urological device including a valve retained in a urinary catheter COLOPLAST A/S (DK) 2023-06-20 US disclosed
US-9993327-B2 Urological device having a bladder retainer and a valve COLOPLAST A/S (DK) 2018-06-12 US disclosed
US-9987112-B2 Method of treating urinary incontinence COLOPLAST A/S (DK) 2018-06-05 US disclosed
US-20170196675-A1 UROLOGICAL DEVICE HAVING A BLADDER RETAINER AND A VALVE COLOPLAST A/S (DK) 2017-07-13 US disclosed
US-9585740-B2 Urological device COLOPLAST A/S (DE) 2017-03-07 US disclosed
US-20170020645-A1 METHOD OF TREATING URINARY INCONTINENCE COLOPLAST A/S (DK) 2017-01-26 US disclosed
US-9498314-B2 Urological device COLOPLAST A/S (DK) 2016-11-22 US disclosed
US-20160317279-A1 VALVE COLOPLAST A/S (DK) 2016-11-03 US disclosed
US-20160184075-A1 BIOMATERIAL COLOPLAST A/S (DK) 2016-06-30 US disclosed
US-20160113750-A1 UROLOGICAL DEVICE VYSERA BIOMEDICAL LIMITED (IE) 2016-04-28 US disclosed
US-20110190905-A1 GASTROINTESTINAL IMPLANT VYSERA BIOMEDICAL LIMITED (IE) 2011-08-04 US disclosed
US-20110160836-A1 VALVE DEVICE VYSERA BIOMEDICAL LIMITED (IE) 2011-06-30 US disclosed
US-20110160706-A1 UROLOGICAL DEVICE VYSERA BIOMEDICAL LIMITED (IE) 2011-06-30 US disclosed
US-20110153027-A1 Drug Delivery System VYSERA BIOMEDICAL LIMITED (IE) 2011-06-23 US disclosed
US-20110152395-A1 Biomaterial VYSERA BIOMEDICAL LIMITED (IE) 2011-06-23 US disclosed
US-7932343-B2 Biomaterial VYSERA BIOMEDICAL LIMITED (IE) 2011-04-26 US disclosed
US-20100137998-A1 ESOPHAGEAL VALVE VYSERA BIOMEDICAL LIMITED (IE) 2010-06-03 US disclosed
US-20100120934-A1 BIOMATERIAL VYSERA BIOMEDICAL LIMITED (IE) 2010-05-13 US disclosed
US-20100121462-A1 VALVE VYSERA BIOMEDICAL LIMITED (IE) 2010-05-13 US disclosed
US-20100121461-A1 VALVE VYSERA BIOMEDICAL LIMITED (IE) 2010-05-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110152395-A1 Biomaterial FGB, BMP2, CCL11 TDP1 588/4885
US-20110153027-A1 Drug Delivery System ERBB3, MATR3, ABCB11 TDP1 1094/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.