Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 1/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | APAF1 | O14727 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL77563 | 0.72 | CES1 (0.70) | AKR1B1CES2CES1L3MBTL1TDP1 | |
| SCHEMBL28605799 | 0.72 | PNMT (0.54) | SRD5A2AKR1B1CES2CES1L3MBTL1 | |
| SCHEMBL19985653 | 0.72 | ALDH1A1 (0.50) | L3MBTL1TDP1MAPTALDH1A1KMT2A | |
| SCHEMBL13930985 | 0.71 | SRD5A2 (0.41) | SRD5A2AKR1B1ALDH1A1KMT2APPARG | |
| Hydrochloric Acid SCHEMBL27690655 | 0.70 | CES1 (0.67) | AKR1B1CES2CES1L3MBTL1TDP1 | |
| SCHEMBL9693670 | 0.70 | CES1 (0.67) | AKR1B1CES2CES1L3MBTL1TDP1 | |
| SCHEMBL12401716 | 0.70 | SRD5A2 (0.49) | SRD5A2CES1ALDH1A1PPARGCYP2C9 | |
| SCHEMBL13930987 | 0.69 | AKR1B1 (0.46) | SRD5A2AKR1B1MAPTALDH1A1MEN1 | |
| SCHEMBL13930983 | 0.69 | ALDH1A1 (0.40) | SRD5A2L3MBTL1TDP1MAPTALDH1A1 | |
| SCHEMBL714287 | 0.68 | HSD11B1 (0.54) | SRD5A2CES1ALDH1A1PPARGCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100099732-A1 | MEDICAMENTS USEFUL AS POTASSIUM CHANNEL MODULATORS | NEUROSEARCH A/S (DK) | 2010-04-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100099732-A1 | MEDICAMENTS USEFUL AS POTASSIUM CHANNEL MODULATORS | KCNN2, KCNN1, KCNN3 | SRD5A2 3400/4885AKR1B1 1385/4885CES2 2979/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.