Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 2/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | NPY4R | P50391 | 2/20 | 0.32 |
| ▸ | NPY1R | P25929 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13396391 | 0.90 | NOS1 (0.34) | NOS1NOS3NOS2NPY4RNPY1R | |
| SCHEMBL13396344 | 0.90 | CA12 (0.36) | NOS1NOS3NOS2NPY4RNPY1R | |
| SCHEMBL13396394 | 0.89 | CA12 (0.36) | NOS1NOS3NOS2NPY4RNPY1R | |
| SCHEMBL13396449 | 0.89 | CA12 (0.36) | NOS1NOS3NOS2NPY4RNPY1R | |
| SCHEMBL13396395 | 0.88 | NOS1 (0.33) | NOS1NOS3NOS2NPY4RNPY1R | |
| SCHEMBL13396385 | 0.87 | NOS1 (0.41) | NOS1NOS3NOS2NPY4RNPY1R | |
| SCHEMBL9741281 | 0.83 | EPHX2 (0.34) | NOS1NOS3NOS2NPY4RNPY1R | |
| SCHEMBL3203673 | 0.80 | NOS1 (0.38) | NOS1NOS3NOS2NPY4RNPY1R | |
| SCHEMBL13396374 | 0.80 | DPP7 (0.44) | NOS1NOS3NOS2NPY4RNPY1R | |
| SCHEMBL13416888 | 0.80 | NPY4R (0.33) | NOS1NOS3NOS2NPY4RNPY1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9266820-B2 | Nitric oxide donor compounds | NICOX SCIENCE IRELAND (IE) | 2016-02-23 | — | — | US | disclosed |
| US-20140288142-A1 | NITRIC OXIDE DONOR COMPOUNDS | NICOX SA (FR) | 2014-09-25 | — | — | US | disclosed |
| US-20100099729-A1 | NITRIC OXIDE DONOR COMPOUNDS | NICOX S.A. (FR) | 2010-04-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140288142-A1 | NITRIC OXIDE DONOR COMPOUNDS | NOS3, NOS2, NOS1 | NOS1 3/4885NOS3 1/4885NOS2 2/4885 |
| US-20100099729-A1 | NITRIC OXIDE DONOR COMPOUNDS | NOS3, NOS2, NOS1 | NOS1 3/4885NOS3 1/4885NOS2 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.