Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY4R | P50391 | 5/20 | 0.33 |
| ▸ | NPY1R | P25929 | 3/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
| ▸ | NPY2R | P49146 | 2/20 | 0.31 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.31 |
| ▸ | OTC | P00480 | 1/20 | 0.30 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13416559 | 0.90 | NOD1 (0.34) | NPY4RNPY1RNOS3NOS1NOS2 | |
| SCHEMBL13416558 | 0.90 | NPY4R (0.34) | NPY4RNPY1RNOS3NOS1NOS2 | |
| SCHEMBL14135402 | 0.88 | NOD1 (0.36) | NPY4RNPY1RNPY2RNPY5ROTC | |
| SCHEMBL13416563 | 0.88 | NOD1 (0.36) | NPY4RNPY1RNPY2RNPY5ROTC | |
| SCHEMBL13416748 | 0.87 | NPY4R (0.33) | NPY4RNPY1RNPY2RNPY5ROTC | |
| SCHEMBL13416746 | 0.86 | DPP7 (0.40) | NPY4RNPY1RNOS1NPY2RNPY5R | |
| SCHEMBL9741281 | 0.85 | EPHX2 (0.34) | NPY4RNPY1RNOS3NOS1NOS2 | |
| SCHEMBL8414057 | 0.82 | NPY4R (0.38) | NPY4RNPY1RNPY2RNPY5ROTC | |
| SCHEMBL13541443 | 0.81 | NOD1 (0.40) | NPY4RNPY1RNPY2RNPY5ROTC | |
| SCHEMBL28718702 | 0.81 | DPP7 (0.39) | NPY4RNPY1RNPY2RNPY5ROTC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100099729-A1 | NITRIC OXIDE DONOR COMPOUNDS | NICOX S.A. (FR) | 2010-04-22 | — | — | US | disclosed |
| WO-2008095841-A2 | NITRIC OXIDE DONOR COMPOUNDS | NICOX S.A. (FR) | 2008-08-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100099729-A1 | NITRIC OXIDE DONOR COMPOUNDS | NOS3, NOS2, NOS1 | NPY4R 1635/4885NPY1R 800/4885NOS3 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.