SCHEMBL13399178

SCHEMBL13399178

CC1(C)OC(=O)C(=C/C=C/N2CCOCC2)C(=O)O1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 14/20 0.44
MAPT P10636 5/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
RECQL P46063 1/20 0.40
APP P05067 1/20 0.38
TSHR P16473 1/20 0.36
GAA P10253 1/20 0.34
NPC1 O15118 4/20 0.33
RAB9A P51151 4/20 0.33
USP2 O75604 3/20 0.33
SMN1; SMN2 Q16637 3/20 0.33
ALOX12 P18054 2/20 0.33
HPGD P15428 2/20 0.33
MEN1 O00255 1/20 0.33
POLB P06746 1/20 0.33
HSP90AA1 P07900 1/20 0.33
MAPK1 P28482 1/20 0.33
KMT2A Q03164 1/20 0.33
HTT P42858 1/20 0.31
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9889302 0.87 ALDH1A1 (0.40) ALDH1A1APPTSHRSMN1; SMN2MAPK1
SCHEMBL19240060 0.79 ALDH1A1 (0.67) ALDH1A1MAPTL3MBTL1RECQLAPP
SCHEMBL19240072 0.74 KMT2A (0.45) ALDH1A1MAPTL3MBTL1RECQLAPP
SCHEMBL14582090 0.68 KMT2A (0.33) ALDH1A1MAPTL3MBTL1RECQLTSHR
SCHEMBL12260834 0.68 ALDH1A1 (0.66) ALDH1A1APPTSHRGAARAB9A
SCHEMBL19240043 0.67 RECQL (0.39) ALDH1A1MAPTL3MBTL1RECQLGAA
SCHEMBL14574020 0.66 ALDH1A1 (0.62) ALDH1A1APPTSHRGAARAB9A
SCHEMBL19240091 0.65 MAPT (0.50) ALDH1A1MAPTL3MBTL1RECQLGAA
SCHEMBL9889241 0.65 APP (0.50) ALDH1A1MAPTL3MBTL1RECQLAPP
SCHEMBL19240004 0.65 ALDH1A1 (0.48) ALDH1A1MAPTL3MBTL1APPGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8535648-B2 Stabilization of UV-sensitive active ingredients BASF SE (DE) 2013-09-17 US disclosed
US-8535648-B2 Stabilization of UV-sensitive active ingredients BASF SE (DE) 2013-09-17 US disclosed
EP-2120854-B1 STABILIZATION OF UV-SENSITIVE ACTIVE INGREDIENTS BASF SE (DE) 2012-12-26 EP disclosed
US-20100104523-A1 STABILIZATION OF UV-SENSITIVE ACTIVE INGREDIENTS CIBA CORPORATION (US) 2010-04-29 US disclosed
US-20100104523-A1 STABILIZATION OF UV-SENSITIVE ACTIVE INGREDIENTS CIBA CORPORATION (US) 2010-04-29 US disclosed
WO-2008090066-A2 STABILIZATION OF UV-SENSITIVE ACTIVE INGREDIENTS CIBA HOLDING INC. (CH) 2008-07-31 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100104523-A1 STABILIZATION OF UV-SENSITIVE ACTIVE INGREDIENTS CRY1, CRYZ, ERCC1 ALDH1A1 272/4885MAPT 441/4885L3MBTL1 3272/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.