SCHEMBL9889302

SCHEMBL9889302

CC1(C)OC(=O)C(=C/C=C/N2CCCCC2)C(=O)O1

nearest known ligand 0.40

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 13/20 0.40
APP P05067 1/20 0.39
SMN1; SMN2 Q16637 2/20 0.35
TSHR P16473 1/20 0.34
HSD17B10 Q99714 2/20 0.33
LMNA P02545 1/20 0.33
HTT P42858 1/20 0.33
CYP1A2 P05177 3/20 0.32
CYP3A4 P08684 1/20 0.32
CRHBP P24387 1/20 0.32
CRHR2 Q13324 1/20 0.32
CYP2C9 P11712 3/20 0.31
CYP2C19 P33261 1/20 0.31
MAPK1 P28482 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13399178 0.87 ALDH1A1 (0.44) ALDH1A1APPSMN1; SMN2TSHRHSD17B10
SCHEMBL19240074 0.76 ALDH1A1 (0.46) ALDH1A1APPSMN1; SMN2LMNAHTT
SCHEMBL19240076 0.74 ALDH1A1 (0.47) ALDH1A1APPSMN1; SMN2LMNAHTT
SCHEMBL9889246 0.73 MEN1 (0.31) ALDH1A1
SCHEMBL19240051 0.70 MAPT (0.45) ALDH1A1APPSMN1; SMN2HTTCYP1A2
SCHEMBL12226903 0.70 PTPN1 (0.39) ALDH1A1SMN1; SMN2HSD17B10LMNAHTT
SCHEMBL19240052 0.68 MAPT (0.43) ALDH1A1APPSMN1; SMN2CYP1A2CYP3A4
SCHEMBL14606486 0.68 APP (0.36) ALDH1A1APPSMN1; SMN2TSHRLMNA
SCHEMBL9889241 0.67 APP (0.50) ALDH1A1APPSMN1; SMN2TSHRLMNA
SCHEMBL19038901 0.67 ALDH1A1 (0.47) ALDH1A1APPSMN1; SMN2HSD17B10LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8652364-B2 Polymer film, ultraviolet absorber, merocyanine compound and process for preparing merocyanine compound FUJIFILM CORPORATION (JP) 2014-02-18 US disclosed
US-8652364-B2 Polymer film, ultraviolet absorber, merocyanine compound and process for preparing merocyanine compound FUJIFILM CORPORATION (JP) 2014-02-18 US disclosed
US-20120140161-A1 POLYMER FILM, RETARDATION FILM, POLARIZING PLATE, LIQUID CRYSTAL DISPLAY DEVICE AND ULTRAVIOLET ABSORBER FUJIFILM CORPORATION (JP) 2012-06-07 US disclosed
US-20120140161-A1 POLYMER FILM, RETARDATION FILM, POLARIZING PLATE, LIQUID CRYSTAL DISPLAY DEVICE AND ULTRAVIOLET ABSORBER FUJIFILM CORPORATION (JP) 2012-06-07 US disclosed
US-20110229662-A1 Polymer film, production method for the film, and retardation film, polarizing plate and liquid-crystal display device having the film FUJIFILM CORPORATION (JP) 2011-09-22 US disclosed
US-20110229662-A1 Polymer film, production method for the film, and retardation film, polarizing plate and liquid-crystal display device having the film FUJIFILM CORPORATION (JP) 2011-09-22 US disclosed
US-20110220843-A1 POLYMER FILM, ULTRAVIOLET ABSORBER, MEROCYANINE COMPOUND AND PROCESS FOR PREPARING MEROCYANINE COMPOUND FUJIFILM CORPORATION (JP) 2011-09-15 US disclosed
US-20110220843-A1 POLYMER FILM, ULTRAVIOLET ABSORBER, MEROCYANINE COMPOUND AND PROCESS FOR PREPARING MEROCYANINE COMPOUND FUJIFILM CORPORATION (JP) 2011-09-15 US disclosed
EP-1441254-B1 Photothermographic material FUJIFILM CORP (JP) 2007-03-28 EP disclosed
EP-1742105-A2 Photothermographic material Fuji Photo Film Co., Ltd. (JP) 2007-01-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110220843-A1 POLYMER FILM, ULTRAVIOLET ABSORBER, MEROCYANINE COMPOUND AND PROCESS FOR PREPARING MEROCYANINE COMPOUND HAMP, CRY1, CRY2 ALDH1A1 1899/4885APP 97/4885SMN1; SMN2 3323/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.