Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.44 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.44 |
| ▸ | TLR2 | O60603 | 4/20 | 0.40 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.38 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.38 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.38 |
| ▸ | RRM1 | P23921 | 1/20 | 0.37 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.36 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.36 |
| ▸ | NMT2 | O60551 | 1/20 | 0.35 |
| ▸ | NMT1 | P30419 | 1/20 | 0.35 |
| ▸ | CPB2 | Q96IY4 | 3/20 | 0.35 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25556371 | 0.82 | MMP1 (0.40) | SIRT6SIRT1GNAI3GNAO1GNAI1 | |
| SCHEMBL13997595 | 0.82 | SIRT6 (0.46) | SIRT6SIRT1TLR2GNAI3GNAO1 | |
| SCHEMBL22330612 | 0.81 | KISS1R (0.43) | SIRT6SIRT1TLR2DPP7RRM1 | |
| SCHEMBL23514658 | 0.81 | SIRT6 (0.58) | SIRT6SIRT1TLR2GNAI3GNAO1 | |
| SCHEMBL569594 | 0.80 | FOLH1 (0.49) | FOLH1CPB2SLC6A5 | |
| SCHEMBL161214 | 0.80 | FOLH1 (0.49) | FOLH1CPB2SLC6A5 | |
| SCHEMBL6848366 | 0.80 | HDAC7 (0.40) | SIRT6SIRT1DPP7CA1CA2 | |
| SCHEMBL14143227 | 0.80 | TSHR (0.32) | SIRT6SIRT1DPP7RRM1 | |
| SCHEMBL13958540 | 0.80 | HDAC7 (0.40) | SIRT6SIRT1DPP7CA1CA2 | |
| SCHEMBL161213 | 0.80 | FOLH1 (0.49) | FOLH1CPB2SLC6A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8404216-B2 | Dendritic chelated compounds, methods for making the same and pharmaceutical compositions containing the same | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2013-03-26 | — | — | US | disclosed |
| US-20100104512-A1 | Dendritic Chelated Compounds, Methods for Making the Same and Pharmaceutical Compositions Containing the Same | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2010-04-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100104512-A1 | Dendritic Chelated Compounds, Methods for Making the Same and Pharmaceutical Compositions Containing the Same | ZYX, CXCR4, ZFX | SIRT6 3653/4885SIRT1 3071/4885TLR2 792/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.