Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CCR6 | P51684 | 1/20 | 0.42 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1285759 | 0.85 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2MAPTHPGDABCB1 | |
| SCHEMBL13397665 | 0.82 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2MAPTHPGDABCB1 | |
| SCHEMBL13300890 | 0.82 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2MAPTHPGDABCB1 | |
| SCHEMBL23944461 | 0.82 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2MAPTHPGDABCB1 | |
| SCHEMBL25901621 | 0.80 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2MAPTHPGDABCB1 | |
| SCHEMBL7694380 | 0.78 | ALDH1A1 (0.62) | ALDH1A1MAPTHPGDABCB1LMNA | |
| SCHEMBL22326382 | 0.78 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2MAPTHPGDABCB1 | |
| SCHEMBL22780788 | 0.78 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2MAPTHPGDABCB1 | |
| SCHEMBL13321683 | 0.76 | AKT1 (0.47) | ALDH1A1SMN1; SMN2MAPTHPGDLMNA | |
| SCHEMBL26296065 | 0.75 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2MAPTHPGDABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023178299-A1 | PRODRUGS OF GANAXOLONE | MARINUS PHARMACEUTICALS, INC. (US) | 2023-09-21 | — | — | WO | disclosed |
| US-8481683-B2 | Human antibodies that bind CD22 and uses thereof | MEDAREX, INC. (US) | 2013-07-09 | — | — | US | disclosed |
| US-8461117-B2 | Chemical linkers and cleavable substrates and conjugates thereof | MEDAREX, INC. (US) | 2013-06-11 | — | — | US | disclosed |
| US-8399403-B2 | drug-ligand conjugates that are potent cytotoxins; stabilized therapeutic agents and markers; exhibit high specificity of action, reduced toxicity, and improved stability in blood ; antitumors | MEDAREX, INC. (US) | 2013-03-19 | — | — | US | disclosed |
| US-20100150950-A1 | HUMAN ANTIBODIES THAT BIND CD70 AND USES THEREOF | MEDAREX, INC. (US) | 2010-06-17 | — | — | US | disclosed |
| US-20100145036-A1 | CHEMICAL LINKERS AND CLEAVABLE SUBSTRATES AND CONJUGATES THEREOF | MEDAREX, INC. (US) | 2010-06-10 | — | — | US | disclosed |
| US-20100143368-A1 | Human Antibodies That Bind Cd22 And Uses Thereof | E. R. SQUIBB & SONS, L.L.C. | 2010-06-10 | — | — | US | disclosed |
| US-20100092496-A1 | CHEMICAL LINKERS AND CONJUGATES THEREOF | MEDAREX, INC. (US) | 2010-04-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100150950-A1 | HUMAN ANTIBODIES THAT BIND CD70 AND USES THEREOF | CD2BP2, CD74, CD63 | ALDH1A1 3203/4885SMN1; SMN2 4036/4885MAPT 4512/4885 |
| US-20100143368-A1 | Human Antibodies That Bind Cd22 And Uses Thereof | CD2BP2, CD22, CD2 | ALDH1A1 1167/4885SMN1; SMN2 1542/4885MAPT 3906/4885 |
| US-20100092496-A1 | CHEMICAL LINKERS AND CONJUGATES THEREOF | CLSPN, CD74, ANTXR2 | ALDH1A1 2165/4885SMN1; SMN2 3628/4885MAPT 4080/4885 |
| US-20100145036-A1 | CHEMICAL LINKERS AND CLEAVABLE SUBSTRATES AND CONJUGATES THEREOF | XIAP, ADAM8, CLSPN | ALDH1A1 2684/4885SMN1; SMN2 2901/4885MAPT 4143/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.