SCHEMBL13402784

CCC(C)[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H]1CCCN1C(=O)C1CCCN1C(=O)[C@H](C)NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)N[C@@H](CSCNC(C)=O)C(=O)N[C@@H](CC(=O)O)C(=O)C[C@@H](CO)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](CC(C)C)C(=O)NC(CCC(=O)O)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](C)C(C)=O)C(C)C

nearest known ligand 0.51

Predicted protein targets (top 8)

	gene	UniProt	supporting neighbours	confidence
▸	TFPI	P10646	9/20	0.51

▸	EP300	Q09472	1/20	0.51

▸	HIF1A	Q16665	1/20	0.51

▸	NPY2R	P49146	7/20	0.49

▸	NPY4R	P50391	7/20	0.49

▸	NPY5R	Q15761	7/20	0.49

▸	NPY1R	P25929	5/20	0.49

▸	KDM1A	O60341	1/20	0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL16326684	1.00	TFPI (0.51)	TFPIEP300HIF1ANPY2RNPY4R
SCHEMBL13402781	0.88	TFPI (0.45)	TFPIEP300HIF1ANPY2RNPY4R
SCHEMBL13402776	0.88	TFPI (0.46)	TFPIEP300HIF1ANPY2RNPY4R
SCHEMBL16326728	0.83	EP300 (0.41)	TFPIEP300HIF1ANPY2RNPY4R
SCHEMBL30445217	0.77	AGTR2 (0.57)	NPY2RNPY4RNPY5RNPY1R
SCHEMBL30432537	0.77	KDM1A (0.55)	TFPINPY2RNPY4RNPY5RNPY1R
Trifluoroacetic Acid SCHEMBL29411175	0.76	TFPI (0.61)	TFPINPY2RNPY4RNPY5RNPY1R
SCHEMBL29693008	0.75	OPRM1 (0.50)	—
SCHEMBL30432635	0.75	NPY2R (0.64)	TFPIEP300HIF1ANPY2RNPY4R
SCHEMBL31182866	0.74	NPY2R (0.63)	EP300HIF1ANPY2RNPY4RNPY5R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-20100081786-A1	Homogeneous Erythropoietin and Other Peptides and Proteins, Methods and Intermediates for Their Preparation	NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT	2010-04-01	—	—	US	disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

Patent	Title	Text reads most about	Predicted target · text-rank
US-20100081786-A1	Homogeneous Erythropoietin and Other Peptides and Proteins, Methods and Intermediates for Their Preparation	EPOR, LIFR, LNPEP	TFPI 4255/4885EP300 4604/4885HIF1A 91/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.