SCHEMBL30445217

SCHEMBL30445217

CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CC(=O)O)NC(=O)OCC1c2ccccc2-c2ccccc21)C(C)C)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)O

nearest known ligand 0.57

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
AGTR2 P50052 3/20 0.57
AGTR1 P30556 2/20 0.57
F2 P00734 4/20 0.54
EPHA2 P29317 2/20 0.54
C5AR1 P21730 2/20 0.52
APLNR P35414 1/20 0.50
CALCR P30988 4/20 0.49
NTSR2 O95665 1/20 0.48
NTSR1 P30989 1/20 0.48
NPY1R P25929 1/20 0.48
NPY2R P49146 1/20 0.48
NPY4R P50391 1/20 0.48
NPY5R Q15761 1/20 0.48
GLP1R P43220 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14520487 0.90 AGTR2 (0.63) AGTR2AGTR1F2EPHA2C5AR1
Angiotensin Ii SCHEMBL29757879 0.90 AGTR2 (0.69) AGTR2AGTR1F2EPHA2C5AR1
Angiotensin Ii SCHEMBL9013950 0.90 AGTR2 (0.69) AGTR2AGTR1F2EPHA2C5AR1
SCHEMBL30445863 0.90 AGTR2 (0.69) AGTR2AGTR1F2EPHA2C5AR1
Angiotensin Ii SCHEMBL9013957 0.90 AGTR2 (0.69) AGTR2AGTR1F2EPHA2C5AR1
Angiotensin Ii SCHEMBL22125774 0.90 AGTR2 (0.69) AGTR2AGTR1F2EPHA2C5AR1
Angiotensin Ii SCHEMBL30960106 0.89 AGTR2 (0.68) AGTR2AGTR1F2EPHA2C5AR1
Angiotensin Ii SCHEMBL28966994 0.89 AGTR2 (0.68) AGTR2AGTR1F2EPHA2C5AR1
SCHEMBL34469957 0.89 AGTR1 (0.62) AGTR2AGTR1F2EPHA2C5AR1
SCHEMBL24454648 0.88 AGTR2 (0.69) AGTR2AGTR1F2EPHA2C5AR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230173076-A1 METABOLICALLY STABLE PEPTIDE ANALOGS UNIV STRASBOURG (FR) 2023-06-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230173076-A1 METABOLICALLY STABLE PEPTIDE ANALOGS GPR119, GLP1R, GIPR AGTR2 110/4885AGTR1 106/4885F2 3392/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.