SCHEMBL134029

SCHEMBL134029

CC[Si](Cl)(CC)c1ccc(C(C)C)cc1

nearest known ligand 0.36

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 2/20 0.36
NFKB1 P19838 1/20 0.36
TYR P14679 2/20 0.35
HTT P42858 2/20 0.33
NOS3 P29474 2/20 0.33
NOS1 P29475 2/20 0.33
NOS2 P35228 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
LMNA P02545 1/20 0.33
NPC1 O15118 2/20 0.33
RAB9A P51151 2/20 0.33
HTR1D P28221 1/20 0.33
HTR1B P28222 1/20 0.33
NOTUM Q6P988 3/20 0.32
USP5 P45974 1/20 0.32
TP53 P04637 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
ADRB2 P07550 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL706051 0.83 ESR1 (0.40)
SCHEMBL19450215 0.77 IDO1 (0.39) IDO1NFKB1TYRHTTNOS3
SCHEMBL136168 0.77 TYR (0.41) IDO1NFKB1TYRHTTSMN1; SMN2
SCHEMBL5032278 0.75 ACHE (0.40) IDO1NPC1RAB9ATP53
SCHEMBL8424443 0.73 NFKB1 (0.38) IDO1NFKB1TYRHTTSMN1; SMN2
SCHEMBL703207 0.72 TP53 (0.38) LMNATP53
SCHEMBL10319964 0.70 NFKB1 (0.36) NFKB1TYRHTTSMN1; SMN2LMNA
SCHEMBL1395155 0.70 LPL (0.42) HTTLMNANPC1RAB9AHTR1D
SCHEMBL104124 0.69 TYR (0.58) IDO1NFKB1TYRHTTLMNA
SCHEMBL13084774 0.69 TYR (0.42) IDO1NFKB1TYRHTTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230205105-A1 TONER, IMAGE FORMING APPARATUS, IMAGE FORMATION METHOD, AND PRINTED MATTER MANUFACTURING METHOD RICOH COMPANY, LTD. (JP) 2023-06-29 US disclosed
US-9152064-B2 Method of preparing developer, developer for electrophotography, process cartridge and image forming apparatus RICOH COMPANY, LTD. (JP) 2015-10-06 US disclosed
US-8886062-B2 Image forming apparatus and image forming method RICOH COMPANY, LTD. (JP) 2014-11-11 US disclosed
US-8778587-B2 Carrier for electrostatic latent image developer, electrostatic latent image developer formed of carrier and toner, and process cartridge using the developer RICOH COMPANY, LTD. (JP) 2014-07-15 US disclosed
US-8722305-B2 Method of preparing carrier for electrophotography RICOH COMPANY, LTD. (JP) 2014-05-13 US disclosed
US-20140080045-A1 METHOD OF PREPARING DEVELOPER, DEVELOPER FOR ELECTROPHOTOGRAPHY, PROCESS CARTRIDGE AND IMAGE FORMING APPARATUS RICOH COMPANY, LTD. (JP) 2014-03-20 US disclosed
US-8647804-B2 Method of preparing carrier for electrophotography, carrier for electrophotography, developer for electrophotography, process cartridge and image forming apparatus RICOH COMPANY, LTD. (JP) 2014-02-11 US disclosed
US-8637218-B2 Carrier for developing electrostatic latent image and developer RICOH COMPANY, LTD. (JP) 2014-01-28 US disclosed
US-20130101930-A1 CARRIER FOR ELECTROSTATIC LATENT IMAGE DEVELOPER, ELECTROSTATIC LATENT IMAGE DEVELOPER FORMED OF CARRIER AND TONER, AND PROCESS CARTRIDGE USING THE DEVELOPER RICOH COMPANY, LTD. (JP) 2013-04-25 US disclosed
US-20130065175-A1 CARRIER FOR DEVELOPING ELECTROSTATIC LATENT IMAGE AND DEVELOPER RICOH COMPANY, LTD. (JP) 2013-03-14 US disclosed
EP-1276017-A2 Non-magnetic single-component toner, method of preparing the same, and image forming apparatus using the same SEIKO EPSON CORPORATION (JP) 2003-01-15 EP disclosed
US-20020136973-A1 External additive for electrophotographic toner, method for manufacturing the external additive, electrophotographic toner using the external additive, and image forming apparatus using the electrophotographic toner RICOH COMPANY, LTD. (JP) 2002-09-26 US disclosed
EP-1237048-A1 External additive for electrophotographic toner, method for manufacturing the external additive, electrophotographic toner using the external additive, and image forming apparatus using the electrophotographic toner Ricoh Company, Ltd. (JP) 2002-09-04 EP disclosed
US-20020081513-A1 Toner, method for manufacturing the toner, and image forming method and apparatus using the toner RICOH COMPANY LIMITED (JP) 2002-06-27 US disclosed
US-6395443-B2 MIXTURE OF BINDER, COLORING AGENT AND CHARGE CONTROL AGENT RICOH COMPANY, LTD. (JP) 2002-05-28 US disclosed
EP-1204006-A1 External additive for eletrophotographic toner, method for manufacturing the external additive, electrophotographic toner using the external additive, and image forming apparatus using the electrophotographic toner Ricoh Company, Ltd. (JP) 2002-05-08 EP disclosed
EP-1193563-A1 Toner, method for manufacturing the toner, and image forming method and apparatus using the toner Ricoh Company, Ltd. (JP) 2002-04-03 EP disclosed
US-20010041298-A1 Toner for developing electrostatic image and process of preparing same RICOH COMPANY, LTD. (JP) 2001-11-15 US disclosed
US-5716748-A SHELL, CORE POLYMER NIPPON ZEON CO., LTD. (JP) 1998-02-10 US disclosed
US-4985328-A Metal Complex Charge Control Agents HITACHI CHEMICAL CO., LTD. (JP) 1991-01-15 US disclosed