SCHEMBL136168

SCHEMBL136168

CC(C)c1ccc([Si](Cl)(Cl)Cl)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TYR P14679 2/20 0.41
NFKB1 P19838 1/20 0.41
HTT P42858 1/20 0.38
ADRB2 P07550 1/20 0.37
IDO1 P14902 2/20 0.37
NOTUM Q6P988 3/20 0.36
NPC1 O15118 2/20 0.36
RAB9A P51151 2/20 0.36
NPSR1 Q6W5P4 2/20 0.36
TP53 P04637 1/20 0.36
MGLL Q99685 1/20 0.35
KDM4E B2RXH2 2/20 0.35
HPGD P15428 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
NISCH Q9Y2I1 1/20 0.35
LMNA P02545 1/20 0.34
CYP2C9 P11712 2/20 0.34
CYP2D6 P10635 1/20 0.34
HIF1A Q16665 1/20 0.34
MAPK1 P28482 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8424443 0.80 NFKB1 (0.38) TYRNFKB1HTTADRB2IDO1
SCHEMBL15259491 0.80 ADRB2 (0.56) NFKB1HTTADRB2TP53LMNA
SCHEMBL20152222 0.78 CYP19A1 (0.42)
SCHEMBL134029 0.77 IDO1 (0.36) TYRNFKB1HTTADRB2IDO1
SCHEMBL10319964 0.77 NFKB1 (0.36) TYRNFKB1HTTNPC1RAB9A
SCHEMBL104124 0.76 TYR (0.58) TYRNFKB1HTTADRB2IDO1
SCHEMBL6124152 0.76 TYR (0.42) TYRNFKB1HTTIDO1NOTUM
SCHEMBL13084774 0.76 TYR (0.42) TYRNFKB1HTTIDO1NOTUM
SCHEMBL19450215 0.75 IDO1 (0.39) TYRNFKB1HTTIDO1NOTUM
SCHEMBL10319681 0.75 ESR1 (0.38) TYRNFKB1NOTUMRAB9ANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230205105-A1 TONER, IMAGE FORMING APPARATUS, IMAGE FORMATION METHOD, AND PRINTED MATTER MANUFACTURING METHOD RICOH COMPANY, LTD. (JP) 2023-06-29 US disclosed
US-20180219160-A1 BENZOBIS(THIADIAZOLE) DERIVATIVE, INK COMPRISING THE SAME, AND ORGANIC ELECTRONIC DEVICE USING THE SAME UBE INDUSTRIES, LTD. (JP) 2018-08-02 US disclosed
EP-3181569-A1 BENZOBIS(THIADIAZOLE) DERIVATIVE, INK CONTAINING SAME, AND ORGANIC ELECTRONIC DEVICE USING SAME UBE Industries, Ltd. (JP) 2017-06-21 EP disclosed
US-9152064-B2 Method of preparing developer, developer for electrophotography, process cartridge and image forming apparatus RICOH COMPANY, LTD. (JP) 2015-10-06 US disclosed
US-8886062-B2 Image forming apparatus and image forming method RICOH COMPANY, LTD. (JP) 2014-11-11 US disclosed
US-8778587-B2 Carrier for electrostatic latent image developer, electrostatic latent image developer formed of carrier and toner, and process cartridge using the developer RICOH COMPANY, LTD. (JP) 2014-07-15 US disclosed
US-8722305-B2 Method of preparing carrier for electrophotography RICOH COMPANY, LTD. (JP) 2014-05-13 US disclosed
US-20140080045-A1 METHOD OF PREPARING DEVELOPER, DEVELOPER FOR ELECTROPHOTOGRAPHY, PROCESS CARTRIDGE AND IMAGE FORMING APPARATUS RICOH COMPANY, LTD. (JP) 2014-03-20 US disclosed
US-8647804-B2 Method of preparing carrier for electrophotography, carrier for electrophotography, developer for electrophotography, process cartridge and image forming apparatus RICOH COMPANY, LTD. (JP) 2014-02-11 US disclosed
US-8637218-B2 Carrier for developing electrostatic latent image and developer RICOH COMPANY, LTD. (JP) 2014-01-28 US disclosed
US-20010041298-A1 Toner for developing electrostatic image and process of preparing same RICOH COMPANY, LTD. (JP) 2001-11-15 US disclosed
EP-0974871-A1 Toner and developer including the same MITA INDUSTRIAL CO. LTD. (JP) 2000-01-26 EP disclosed
EP-0974870-A1 Toner for amorphous silicon photoreceptor and developer including the same MITA INDUSTRIAL CO. LTD. (JP) 2000-01-26 EP disclosed
US-5997637-A Method of producing a semiconducting material NIPPON OIL CO., LTD. (JP) 1999-12-07 US disclosed
EP-0632086-B1 A method of producing a semiconducting material NIPPON OIL CO LTD (JP) 1999-10-06 EP disclosed
US-5716748-A SHELL, CORE POLYMER NIPPON ZEON CO., LTD. (JP) 1998-02-10 US disclosed
EP-0632086-A2 A method of producing a semiconducting material NIPPON OIL CO., LTD. (JP) 1995-01-04 EP disclosed
US-4985328-A Metal Complex Charge Control Agents HITACHI CHEMICAL CO., LTD. (JP) 1991-01-15 US disclosed
EP-0360617-A2 Dry toner, dry developer and process for forming images Hitachi Chemical Co., Ltd. (JP) 1990-03-28 EP disclosed
US-4686166-A HIGH IMAGE DENSITY, ANTIFOGGING AGENT HITACHI CHEMICAL CO. (JP) 1987-08-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180219160-A1 BENZOBIS(THIADIAZOLE) DERIVATIVE, INK COMPRISING THE SAME, AND ORGANIC ELECTRONIC DEVICE USING THE SAME IKZF3, HELZ, TEC TYR 15/4885NFKB1 3035/4885HTT 3908/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.