Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9513607 | 0.97 | MEN1 (0.34) | MEN1KMT2AGAA | |
| SCHEMBL502245 | 0.87 | MEN1 (0.37) | MEN1KMT2AGAAMAPTHTT | |
| SCHEMBL9787015 | 0.84 | — | — | |
| SCHEMBL9787166 | 0.81 | MEN1 (0.32) | MEN1KMT2AGAA | |
| SCHEMBL10744284 | 0.80 | MEN1 (0.37) | MEN1KMT2AGAAMAPTHTT | |
| Pyridine SCHEMBL10754731 | 0.80 | TSHR (0.41) | MEN1KMT2AGAA | |
| SCHEMBL10870412 | 0.80 | MEN1 (0.31) | MEN1KMT2AGAAMAPTHTT | |
| SCHEMBL8735002 | 0.80 | CES2 (0.31) | — | |
| SCHEMBL10871601 | 0.80 | MEN1 (0.34) | MEN1KMT2AGAA | |
| SCHEMBL7028015 | 0.79 | MEN1 (0.36) | MEN1KMT2AGAAMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 244 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113896679-B | Synthesis method of key intermediate of pyrrole pyridine kinase inhibitor | 合肥利夫生物科技有限公司 | 2024-03-01 | — | — | CN | claimed |
| US-11649232-B2 | Synthetic dimeric cinchona alkaloids against cancer | Ares Pharmaceuticals, LLC (US) | 2023-05-16 | — | — | US | claimed |
| US-20220372029-A1 | SYNTHETIC DIMERIC CINCHONA ALKALOIDS AGAINST CANCER | Ares Pharmaceuticals, LLC (US) | 2022-11-24 | — | — | US | claimed |
| CN-113896679-A | Synthesis method of key intermediate of pyrrole pyridine kinase inhibitor | 合肥利夫生物科技有限公司 | 2022-01-07 | — | — | CN | claimed |
| EP-3149020-A2 | CHEMICALLY MODIFYING PEPTIDES | The University of Durham (GB) | 2017-04-05 | — | — | EP | claimed |
| EP-3149021-A1 | CYCLISING PEPTIDES | The University of Durham (GB) | 2017-04-05 | — | — | EP | claimed |
| WO-2015181544-A2 | CHEMICALLY MODIFYING PEPTIDES | THE UNIVERSITY OF DURHAM (GB) | 2015-12-03 | — | — | WO | claimed |
| WO-2015181545-A1 | CYCLISING PEPTIDES | THE UNIVERSITY OF DURHAM (GB) | 2015-12-03 | — | — | WO | claimed |
| US-8952083-B2 | Fluorocopolymer composition and its production process | ASAHI GLASS COMPANY, LIMITED (JP) | 2015-02-10 | — | — | US | claimed |
| WO-2000044724-A1 | IMPROVED METHOD FOR THE PREPARATION OF 3,5-DICHLORO-2,4,6-TRIFLUOROPYRIDINE | MAKHTESHIM CHEMICAL WORKS LTD. (IL) | 2000-08-03 | — | — | WO | claimed |
| EP-0491688-A4 | METHODS FOR ACTIVATING POLYMERIC CARRIERS AND COMPOSITIONS PREPARED THEREFROM FOR USE IN AFFINITY CHROMATOGRAPHY | — | 1993-03-10 | — | — | EP | claimed |
| EP-0491688-A1 | METHODS FOR ACTIVATING POLYMERIC CARRIERS AND COMPOSITIONS PREPARED THEREFROM FOR USE IN AFFINITY CHROMATOGRAPHY. | BIOPROBE INT INC (US) | 1992-07-01 | — | — | EP | claimed |
| WO-1991003257-A1 | METHODS FOR ACTIVATING POLYMERIC CARRIERS AND COMPOSITIONS PREPARED THEREFROM FOR USE IN AFFINITY CHROMATOGRAPHY | BIOPROBE INTERNATIONAL, INC. (US) | 1991-03-21 | — | — | WO | claimed |
| US-4999432-A | Heating and dechlorination of a chloropyridine | DOWELANCO (US) | 1991-03-12 | — | — | US | claimed |
| EP-0415498-A2 | Fluorination with hydrogen fluoride | DOWELANCO (US) | 1991-03-06 | — | — | EP | claimed |
| US-4981961-A | Chemically-stable chromatography adsorber; modifying nucleophilic polymers with pyridine bases | BIOPROBE INTERNATIONAL, INC. (US) | 1991-01-01 | — | — | US | claimed |
| EP-0270221-A1 | Method of preparation of 3,5-dichloro-2,4,6-trifluoropyridine | DOWELANCO (US) | 1988-06-08 | — | — | EP | claimed |
| US-4746744-A | Method of preparation of 3,5-dichloro-2,4,6-trifluoropyridine | THE DOW CHEMICAL COMPANY (US) | 1988-05-24 | — | — | US | claimed |
| EP-0192287-A2 | Process for the preparation of fluorinated pyridines | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1986-08-27 | — | — | EP | claimed |
| US-4542221-A | Exchanging fluorine for chlorine in a chlorinated pyridine with an alkali metal fluoride | THE DOW CHEMICAL COMPANY (US) | 1985-09-17 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11649232-B2 | Synthetic dimeric cinchona alkaloids against cancer | BAD, MCL1, BCL9 | MEN1 140/4885KMT2A 462/4885GAA 1063/4885 |
| US-20220372029-A1 | SYNTHETIC DIMERIC CINCHONA ALKALOIDS AGAINST CANCER | BAD, MCL1, BCL9 | MEN1 140/4885KMT2A 462/4885GAA 1063/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.