SCHEMBL1340459

SCHEMBL1340459

O=[N+]([O-])c1ccccc1Oc1ccccc1F

nearest known ligand 0.71

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HSPB1 P04792 3/20 0.71
L3MBTL1 Q9Y468 1/20 0.64
HPGD P15428 1/20 0.64
ALDH1A1 P00352 2/20 0.56
TDP1 Q9NUW8 2/20 0.56
MAPT P10636 2/20 0.55
PIN1 Q13526 1/20 0.55
NPC1 O15118 1/20 0.55
RECQL P46063 1/20 0.55
RAB9A P51151 1/20 0.55
MEN1 O00255 2/20 0.52
KMT2A Q03164 2/20 0.52
ESR2 Q92731 1/20 0.51
SMN1; SMN2 Q16637 1/20 0.49
POLB P06746 1/20 0.49
HTT P42858 1/20 0.49
GAA P10253 1/20 0.47
ATM Q13315 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL39472 0.88 HPGD (0.78) HSPB1L3MBTL1HPGDALDH1A1TDP1
SCHEMBL3547648 0.86 HSPB1 (0.64) HSPB1L3MBTL1HPGDALDH1A1TDP1
SCHEMBL1341961 0.86 HSPB1 (0.75) HSPB1L3MBTL1HPGDALDH1A1TDP1
SCHEMBL28056476 0.86 L3MBTL1 (0.81) HSPB1L3MBTL1HPGDALDH1A1TDP1
SCHEMBL1338743 0.86 HSPB1 (0.60) HSPB1L3MBTL1HPGDALDH1A1TDP1
SCHEMBL31470009 0.84 HSPB1 (0.68) HSPB1L3MBTL1HPGDALDH1A1TDP1
SCHEMBL3597295 0.82 HSPB1 (0.59) HSPB1L3MBTL1HPGDALDH1A1TDP1
SCHEMBL28317468 0.82 HSPB1 (0.72) HSPB1L3MBTL1HPGDALDH1A1MAPT
SCHEMBL27751259 0.82 HPGD (0.53) HSPB1L3MBTL1HPGDALDH1A1TDP1
SCHEMBL11406237 0.81 HPGD (0.68) HSPB1L3MBTL1HPGDALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114002297-A Dopamine ion carrier, dopamine sensitive membrane containing same, dopamine probe and preparation method 何成 2022-02-01 CN claimed
US-20050006237-A1 Ion-selective solid-state polymeric membrane electrondes REGENTS OF THE UNIVERSITY OF MICHIGAN 2005-01-13 US claimed
EP-1287345-A2 ION-SELECTIVE SOLID-STATE POLYMERIC MEMBRANE ELECTRODES MEDTRONIC, INC. (US) 2003-03-05 EP claimed
WO-2001088520-A2 ION-SELECTIVE SOLID-STATE POLYMERIC MEMBRANE ELECTRODES MEDTRONIC, INC. (US) 2001-11-22 WO claimed
US-20250304571-A1 BIOLOGICALLY ACTIVE COMPOUNDS AND METHODS THEREOF SUZHOU KEEN THERAPEUTICS CO., LTD. (CN) 2025-10-02 US disclosed
EP-4580489-A1 DEVICES AND METHODS FOR MEASURING A CONCENTRATION OF A TARGET ANALYTE IN A BIOLOGICAL FLUID IN VIVO DexCom, Inc. (US) 2025-07-09 EP disclosed
EP-4565588-A1 BIOLOGICALLY ACTIVE COMPOUNDS AND METHODS THEREOF Suzhou Keen Therapeutics Co., Ltd. (CN) 2025-06-11 EP disclosed
CN-119730782-A Apparatus and method for measuring concentration of target analyte in biological fluid in vivo 德克斯康公司 2025-03-28 CN disclosed
US-20240074682-A1 DEVICES AND METHODS FOR MEASURING A CONCENTRATION OF A TARGET ANALYTE IN A BIOLOGICAL FLUID IN VIVO DEXCOM, INC. (US) 2024-03-07 US disclosed
WO-2024050124-A1 DEVICES AND METHODS FOR MEASURING A CONCENTRATION OF A TARGET ANALYTE IN A BIOLOGICAL FLUID IN VIVO DEXCOM, INC. (US) 2024-03-07 WO disclosed
WO-2023241620-A1 BIOLOGICALLY ACTIVE COMPOUNDS AND METHODS THEREOF SUZHOU KEEN THERAPEUTICS CO., LTD. (CN) 2023-12-21 WO disclosed
US-20230329097-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY DEVICE SAMSUNG SDI CO LTD (KR) 2023-10-12 US disclosed
WO-1999002651-A1 OPTICAL FIBERLESS SENSORS THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 1999-01-21 WO disclosed
EP-0300364-B1 CHLORIDE ION-SELECTIVE ELECTRODE HITACHI, LTD. (JP) 1992-09-30 EP disclosed
US-5116481-A ANION-SELECTIVE, SENSITIVE FILM, ELECTRODE CONTAINING THE SAME AND THE USE THEREOF HITACHI, LTD. (JP) 1992-05-26 US disclosed
US-5112471-A Polymer, a nitrophenyl ether plastizer, quaternary ammonium or phosphonium salt HITACHI, LTD. (JP) 1992-05-12 US disclosed
US-4936975-A Chloride ion-selective electrode HITACHI, LTD. (JP) 1990-06-26 US disclosed
EP-0339613-A2 Ion selective electrode HITACHI, LTD. (JP) 1989-11-02 EP disclosed
EP-0300364-A2 Chloride ion-selective electrode HITACHI, LTD. (JP) 1989-01-25 EP disclosed
EP-0059884-B1 BENZOFURANE DERIVATIVES, THEIR PREPARATION AND USE SCHERING AKTIENGESELLSCHAFT (DE) 1985-05-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230329097-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY DEVICE OR10J3, OCIAD2, OCIAD1 HSPB1 3861/4885L3MBTL1 4601/4885HPGD 1901/4885
US-20250304571-A1 BIOLOGICALLY ACTIVE COMPOUNDS AND METHODS THEREOF VHL, BRCA1, TERT HSPB1 2560/4885L3MBTL1 517/4885HPGD 426/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.