Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSPB1 | P04792 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 6/20 | 0.53 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1340459 | 0.82 | HSPB1 (0.71) | HSPB1MAPTPIN1HTTL3MBTL1 | |
| SCHEMBL11274397 | 0.82 | HPGD (0.69) | MAPTPIN1HTTLMNAL3MBTL1 | |
| SCHEMBL1137076 | 0.81 | HSPB1 (0.48) | HSPB1MAPTHTTLMNAL3MBTL1 | |
| SCHEMBL9853797 | 0.80 | ALDH1A1 (0.51) | MAPTPIN1HTTLMNAGAA | |
| SCHEMBL9853600 | 0.80 | PIN1 (0.56) | MAPTPIN1HTTLMNAL3MBTL1 | |
| SCHEMBL1306618 | 0.79 | ALDH1A1 (0.46) | HSPB1MAPTHTTLMNAL3MBTL1 | |
| SCHEMBL16295419 | 0.78 | MAPT (0.54) | HSPB1MAPTHTTLMNAL3MBTL1 | |
| SCHEMBL3547648 | 0.74 | HSPB1 (0.64) | HSPB1MAPTPIN1HTTL3MBTL1 | |
| SCHEMBL27350487 | 0.74 | ALDH1A1 (0.48) | MAPTPIN1HTTLMNAL3MBTL1 | |
| SCHEMBL28317468 | 0.73 | HSPB1 (0.72) | HSPB1MAPTPIN1LMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1784403-B1 | PYRROLO[3,2-B]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORP (KR) | 2013-07-17 | — | — | EP | disclosed |
| CN-101010321-B | Pyrrolo[3,2-B]pyridine derivatives and processes for the preparation thereof | YUHAN CORP | 2011-10-26 | — | — | CN | disclosed |
| US-7642269-B2 | Pyrrolo[3,2-B]pyridine derivatives and processes for the preparation thereof | YUHAN CORPORATION (KR) | 2010-01-05 | — | — | US | disclosed |
| US-20070213358-A1 | PYRROLO[3,2-B]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION (KR) | 2007-09-13 | — | — | US | disclosed |
| CN-101010321-A | Pyrrolo[3,2-B]pyridine derivatives and processes for the preparation thereof | YUHAN CORP (KR) | 2007-08-01 | — | — | CN | disclosed |
| EP-1784403-A1 | PYRROLO[3,2-B]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | Yuhan Corporation (KR) | 2007-05-16 | — | — | EP | disclosed |
| WO-2006038773-A1 | PYRROLO[3,2-B]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION (KR) | 2006-04-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070213358-A1 | PYRROLO[3,2-B]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | PGA5, ATP6AP1, PPOX | HSPB1 2330/4885MAPT 3810/4885PIN1 146/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.