Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 9/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | SMO | Q99835 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13405756 | 0.89 | CSF1R (0.72) | CSF1RKDM4EALDH1A1GAARECQL | |
| SCHEMBL13405754 | 0.86 | CSF1R (0.72) | CSF1RKDM4EALDH1A1GAARECQL | |
| Trifluoroacetic Acid SCHEMBL3540848 | 0.85 | CSF1R (0.66) | CSF1RKDM4EALDH1A1GAA | |
| SCHEMBL13767719 | 0.84 | CSF1R (0.77) | CSF1RKDM4EALDH1A1GAAPOLB | |
| SCHEMBL3540736 | 0.82 | ALDH1A1 (0.55) | CSF1RKDM4EALDH1A1RECQLMEN1 | |
| SCHEMBL3534730 | 0.78 | ALDH1A1 (0.50) | CSF1RKDM4EALDH1A1RECQLMEN1 | |
| Trifluoroacetic Acid SCHEMBL3542661 | 0.77 | ALDH1A1 (0.49) | KDM4EALDH1A1RECQLMEN1MAPT | |
| SCHEMBL3539286 | 0.75 | TDP1 (0.53) | KDM4EALDH1A1GAARECQLMAPT | |
| SCHEMBL3969432 | 0.74 | CSF1R (0.56) | CSF1RKDM4EALDH1A1GAARECQL | |
| SCHEMBL5188971 | 0.72 | ALDH1A1 (0.55) | KDM4EALDH1A1GAARECQLMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1807407-B1 | AROMATIC AMIDES AS INHIBITORS OF C-FMS KINASE | JANSSEN PHARMACEUTICA NV (BE) | 2009-07-29 | — | — | EP | disclosed |