Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 18/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13405756 | 0.95 | CSF1R (0.72) | CSF1RKDM4EGAAALDH1A1 | |
| SCHEMBL13405754 | 0.92 | CSF1R (0.72) | CSF1RKDM4EGAAALDH1A1 | |
| SCHEMBL13767720 | 0.85 | CSF1R (0.56) | CSF1RKDM4EGAAALDH1A1 | |
| SCHEMBL3969432 | 0.81 | CSF1R (0.56) | CSF1RKDM4EGAAALDH1A1 | |
| SCHEMBL13405733 | 0.80 | CSF1R (1.00) | CSF1R | |
| Trifluoroacetic Acid SCHEMBL3542661 | 0.80 | ALDH1A1 (0.49) | KDM4EALDH1A1 | |
| SCHEMBL3544978 | 0.75 | CSF1R (0.79) | CSF1R | |
| Trifluoroacetic Acid SCHEMBL3538114 | 0.75 | CSF1R (0.68) | CSF1R | |
| SCHEMBL13405752 | 0.75 | CSF1R (0.68) | CSF1R | |
| SCHEMBL3540736 | 0.73 | ALDH1A1 (0.55) | CSF1RKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1807407-A1 | AROMATIC AMIDES AS INHIBITORS OF C-FMS KINASE | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-07-18 | — | — | EP | claimed |
| WO-2006047504-A1 | AROMATIC AMIDES AS INHIBITORS OF C-FMS KINASE | JANSSEN PHARMACEUTICA, N.V. (BE) | 2006-05-04 | — | — | WO | claimed |
| US-7705042-B2 | Class of arylamide compounds useful as inhibitors of c-fms kinase | JANSSEN PHARMACEUTICA NV (BE) | 2010-04-27 | — | — | US | disclosed |
| EP-1807407-A1 | AROMATIC AMIDES AS INHIBITORS OF C-FMS KINASE | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-07-18 | — | — | EP | disclosed |
| WO-2006047504-A1 | AROMATIC AMIDES AS INHIBITORS OF C-FMS KINASE | JANSSEN PHARMACEUTICA, N.V. (BE) | 2006-05-04 | — | — | WO | disclosed |