SCHEMBL134063

SCHEMBL134063

c1ccc(-n2c(-c3ccc(-c4cccc5c4ccc4cc6ccccc6cc45)cc3)nc3ccccc32)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 2/20 0.48
ESR2 Q92731 2/20 0.48
RECQL P46063 1/20 0.45
GRIA1 P42261 1/20 0.44
CACNG8 Q8WXS5 1/20 0.44
CACNG2 Q9Y698 1/20 0.44
HTT P42858 2/20 0.42
MAPK1 P28482 1/20 0.42
HDAC1 Q13547 1/20 0.41
HDAC8 Q9BY41 1/20 0.41
HDAC6 Q9UBN7 1/20 0.41
GAA P10253 2/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
ALDH1A1 P00352 6/20 0.41
LMNA P02545 1/20 0.41
PTGS2 P35354 1/20 0.41
RAB9A P51151 2/20 0.40
HSP90AA1 P07900 1/20 0.40
MAPT P10636 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9976937 0.97 ESR1 (0.53) ESR1ESR2RECQLGRIA1CACNG8
SCHEMBL8780813 0.95 ESR1 (0.48) ESR1ESR2RECQLGRIA1CACNG8
SCHEMBL1234985 0.92 ESR1 (0.49) ESR1ESR2RECQLGRIA1CACNG8
SCHEMBL9612379 0.91 ESR1 (0.44) ESR1ESR2RECQLGRIA1CACNG8
SCHEMBL10019158 0.90 ESR1 (0.57) ESR1ESR2RECQLGRIA1CACNG8
SCHEMBL9612374 0.89 ESR1 (0.51) ESR1ESR2RECQLGRIA1CACNG8
SCHEMBL12626752 0.89 ESR1 (0.53) ESR1ESR2RECQLGRIA1CACNG8
SCHEMBL9612416 0.89 ESR1 (0.46) ESR1ESR2RECQLGRIA1CACNG8
SCHEMBL8780510 0.88 ESR1 (0.54) ESR1ESR2RECQLGRIA1CACNG8
SCHEMBL13249114 0.88 ESR1 (0.49) ESR1ESR2RECQLGRIA1CACNG8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 111 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3457450-B1 ORGANIC ELECTROLUMINESCENT DEVICE MERCK PATENT GMBH (DE) 2024-06-12 EP disclosed
US-20230337537-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES UDC IRELAND LIMITED (IE) 2023-10-19 US disclosed
US-20230337537-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES UDC IRELAND LIMITED (IE) 2023-10-19 US disclosed
US-11737354-B2 Organic light emitting device having a carbazole-based compound formed between a cathode and a light emitting layer and a spirobifluorene-monoamine-based compound formed between an anode and a light emitting layer LG CHEM, LTD. (KR) 2023-08-22 US disclosed
US-11737354-B2 Organic light emitting device having a carbazole-based compound formed between a cathode and a light emitting layer and a spirobifluorene-monoamine-based compound formed between an anode and a light emitting layer LG CHEM, LTD. (KR) 2023-08-22 US disclosed
US-20230002416-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES UDC IRELAND LIMITED (IE) 2023-01-05 US disclosed
US-11424418-B2 Metal complex organic electroluminescent material and organic electroluminescent device SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIAL CO., LTD. (CN) 2022-08-23 US disclosed
WO-2021191058-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2021-09-30 WO disclosed
US-20200381633-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIAL CO., LTD. (CN) 2020-12-03 US disclosed
US-20200295264-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2020-09-17 US disclosed
WO-2010136109-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2010-12-02 WO disclosed
WO-2010115498-A1 ORGANIC ELECTROLUMINESCENCE DEVICE MERCK PATENT GMBH (DE) 2010-10-14 WO disclosed
WO-2010108579-A1 ORGANIC ELECTROLUMINESCENT DEVICE MERCK PATENT GMBH (DE) 2010-09-30 WO disclosed
WO-2010102706-A1 ORGANIC ELECTROLUMINESCENCE DEVICE MERCK PATENT GMBH (DE) 2010-09-16 WO disclosed
US-20100187505-A1 BENZANTHRACENE DERIVATIVES FOR ORGANIC ELECTROLUMINESCENT DEVICES IDEMITSU KOSAN CO., LTD. (JP) 2010-07-29 US disclosed
US-20100187505-A1 BENZANTHRACENE DERIVATIVES FOR ORGANIC ELECTROLUMINESCENT DEVICES IDEMITSU KOSAN CO., LTD. (JP) 2010-07-29 US disclosed
US-20100187505-A1 BENZANTHRACENE DERIVATIVES FOR ORGANIC ELECTROLUMINESCENT DEVICES IDEMITSU KOSAN CO., LTD. (JP) 2010-07-29 US disclosed
EP-2148909-A2 NOVEL MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES Merck Patent GmbH (DE) 2010-02-03 EP disclosed
WO-2008145239-A2 BENZANTHRACENE DERIVATIVES FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2008-12-04 WO disclosed
WO-2008145239-A2 BENZANTHRACENE DERIVATIVES FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2008-12-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230337537-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES L1CAM, PIEZO1, GPX1 ESR1 147/4885ESR2 471/4885RECQL 1892/4885
US-20100187505-A1 BENZANTHRACENE DERIVATIVES FOR ORGANIC ELECTROLUMINESCENT DEVICES KCNT1, KCNC1, TMEM109 ESR1 667/4885ESR2 510/4885RECQL 2340/4885
US-20230002416-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES GPX1, L1CAM, TMEM109 ESR1 211/4885ESR2 895/4885RECQL 1289/4885
US-20200295264-A1 ORGANIC LIGHT EMITTING DEVICE TPH1, DRD1, CYP1A1 ESR1 91/4885ESR2 161/4885RECQL 2226/4885
US-11737354-B2 Organic light emitting device having a carbazole-based compound formed between a cathode and a light emitting layer and a spirobifluorene-monoamine-based compound formed between an anode and a light emitting layer DRD1, TPH1, DRD3 ESR1 141/4885ESR2 348/4885RECQL 2226/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.