Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAOX | Q6QHF9 | 5/20 | 0.38 |
| ▸ | PRKCA | P17252 | 2/20 | 0.34 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL835135 | 0.90 | CES2 (0.41) | PRKCAPRKCEALDH1A1 | |
| SCHEMBL28332885 | 0.87 | ALDH1A1 (0.36) | PAOXACHEALDH1A1 | |
| SCHEMBL3746246 | 0.86 | GPR84 (0.44) | ALDH1A1 | |
| SCHEMBL3426528 | 0.85 | ALDH1A1 (0.35) | ALDH1A1 | |
| SCHEMBL13442940 | 0.85 | MAPT (0.40) | PAOX | |
| SCHEMBL13442938 | 0.85 | CNR1 (0.41) | PAOXPRKCAPRKCEALDH1A1 | |
| SCHEMBL863512 | 0.84 | CES2 (0.45) | ALDH1A1 | |
| SCHEMBL19628786 | 0.84 | CES2 (0.45) | ALDH1A1 | |
| SCHEMBL3125935 | 0.82 | TSHR (0.42) | PRKCAPRKCEALDH1A1 | |
| SCHEMBL19628778 | 0.80 | PAOX (0.42) | PAOXPRKCAACHEALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7700792-B2 | Highly active lysophosphatidic acid and method of screening therewith | ONO PHARMACEUTICAL CO., LTD. (JP) | 2010-04-20 | — | — | US | disclosed |
| US-7700792-B2 | Highly active lysophosphatidic acid and method of screening therewith | ONO PHARMACEUTICAL CO., LTD. (JP) | 2010-04-20 | — | — | US | disclosed |
| US-20070161604-A1 | Highly active lysophosphatidic acid and method of screening therewith | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-07-12 | — | — | US | disclosed |
| US-20070161604-A1 | Highly active lysophosphatidic acid and method of screening therewith | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-07-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070161604-A1 | Highly active lysophosphatidic acid and method of screening therewith | LPAR2, LPAR1, LPAR6 | PAOX 340/4885PRKCA 1679/4885PRKCE 2577/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.