Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.34 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.34 |
| ▸ | BTK | Q06187 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 4/20 | 0.34 |
| ▸ | NPC1 | O15118 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.32 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.32 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.32 |
| ▸ | SELE | P16581 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8272622 | 0.89 | GRM1 (0.38) | MAPTGRM1L3MBTL1SMN1; SMN2MEN1 | |
| SCHEMBL8351590 | 0.81 | GRM1 (0.40) | MAPTATMGRM1L3MBTL1SMN1; SMN2 | |
| SCHEMBL3429590 | 0.81 | TYR (0.41) | MAPTATMSMN1; SMN2MEN1KMT2A | |
| SCHEMBL13409339 | 0.78 | APP (0.44) | MAPTATMMEN1KMT2ARAB9A | |
| SCHEMBL13409338 | 0.76 | MAPT (0.41) | MAPTATML3MBTL1SMN1; SMN2BTK | |
| SCHEMBL13409379 | 0.76 | PDGFRB (0.43) | MAPTATMSMN1; SMN2MEN1KMT2A | |
| SCHEMBL13409378 | 0.75 | MAPT (0.46) | MAPTATMSMN1; SMN2MEN1KMT2A | |
| SCHEMBL13409333 | 0.74 | CYP1A1 (0.42) | MAPTATMCYP1A1CYP1B1RAB9A | |
| SCHEMBL13409376 | 0.74 | MAPT (0.55) | MAPTATMSMN1; SMN2MEN1KMT2A | |
| SCHEMBL15692155 | 0.74 | ALDH1A1 (0.44) | MAPTGRM1L3MBTL1SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7705146-B2 | Hepatitis C inhibitor peptide analogs | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-04-27 | — | — | US | disclosed |
| US-7705146-B2 | Hepatitis C inhibitor peptide analogs | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-04-27 | — | — | US | disclosed |