Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | ATM | Q13315 | 2/20 | 0.41 |
| ▸ | BTK | Q06187 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.35 |
| ▸ | NQO2 | P16083 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ACP1 | P24666 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | INSR | P06213 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8273091 | 0.89 | RAB9A (0.41) | MAPTBTKNPC1RAB9ANQO2 | |
| SCHEMBL1536628 | 0.81 | RAB9A (0.40) | MAPTNPC1RAB9ANQO2CYP1A2 | |
| SCHEMBL1536535 | 0.81 | RAB9A (0.46) | MAPTNPC1RAB9ANQO2CYP1A2 | |
| SCHEMBL8353207 | 0.81 | RAB9A (0.40) | MAPTATMNPC1RAB9ANQO2 | |
| SCHEMBL13409376 | 0.80 | MAPT (0.55) | MAPTATMBTKNPC1RAB9A | |
| SCHEMBL13409339 | 0.79 | APP (0.44) | MAPTATMNPC1RAB9AACP1 | |
| SCHEMBL13409378 | 0.78 | MAPT (0.46) | MAPTATMBTKNPC1RAB9A | |
| SCHEMBL13409349 | 0.77 | TRPM8 (0.49) | MAPTATMBTKNPC1RAB9A | |
| SCHEMBL13409341 | 0.76 | MAPT (0.36) | MAPTATMBTKNPC1RAB9A | |
| SCHEMBL13409379 | 0.74 | PDGFRB (0.43) | MAPTATMNPC1RAB9ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7705146-B2 | Hepatitis C inhibitor peptide analogs | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-04-27 | — | — | US | disclosed |