Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 2/20 | 0.40 |
| ▸ | PLG | P00747 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 5/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 5/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.36 |
| ▸ | SELE | P16581 | 1/20 | 0.36 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8271703 | 0.86 | PLAU (0.45) | PLAUPLGPDE4APDE4BPDE4C | |
| SCHEMBL13409361 | 0.84 | TRPM8 (0.41) | TSHRSMN1; SMN2MAPTATMCYP3A4 | |
| SCHEMBL13409358 | 0.78 | MAPT (0.47) | PLAUTSHRSMN1; SMN2MAPTATM | |
| SCHEMBL1536440 | 0.78 | PLAU (0.46) | PLAUPLGPDE4APDE4BPDE4C | |
| SCHEMBL1536456 | 0.74 | PLAU (0.49) | PLAUPLGPDE4APDE4BPDE4C | |
| SCHEMBL17433286 | 0.74 | ACACB (0.43) | LMNACYP2C9TSHRAPEX1SMN1; SMN2 | |
| SCHEMBL13385161 | 0.73 | TRPA1 (0.56) | PLAUCYP2C9MAPTATMCYP3A4 | |
| SCHEMBL13757489 | 0.73 | TRPA1 (0.56) | MAPTATM | |
| SCHEMBL24916397 | 0.72 | P2RX3 (0.42) | LMNACYP2C9TSHRAPEX1SMN1; SMN2 | |
| SCHEMBL3431729 | 0.71 | TRPM8 (0.40) | TSHRSMN1; SMN2MAPTATMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7705146-B2 | Hepatitis C inhibitor peptide analogs | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-04-27 | — | — | US | disclosed |