Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.36 |
| ▸ | ATR | Q13535 | 3/20 | 0.33 |
| ▸ | ATRIP | Q8WXE1 | 2/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.33 |
| ▸ | FEN1 | P39748 | 2/20 | 0.33 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.33 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.32 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.31 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.31 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8271691 | 0.83 | TRPA1 (0.41) | TRPA1MAOAMAOBCYP1A1CYP1A2 | |
| SCHEMBL8274159 | 0.80 | MAOA (0.39) | TRPA1MAOAMAOBCYP1A1CYP1A2 | |
| SCHEMBL13409383 | 0.77 | TRPA1 (0.40) | TRPA1LRRK2 | |
| SCHEMBL8272976 | 0.76 | MAOA (0.39) | TRPA1MAOAMAOBCYP1A1CYP1A2 | |
| SCHEMBL8276162 | 0.75 | MAOA (0.43) | TRPA1MAOAMAOBCYP1A1CYP1A2 | |
| SCHEMBL13409367 | 0.72 | MAPT (0.43) | LRRK2TRPM8CYP1A2 | |
| SCHEMBL16319037 | 0.72 | MAOA (0.57) | MAOAMAOBCYP1A1CYP1A2CYP1B1 | |
| SCHEMBL13409368 | 0.71 | LRRK2 (0.35) | LRRK2ATRATRIPIRAK4 | |
| SCHEMBL13409398 | 0.71 | BAD (0.38) | TRPA1LRRK2CYP1A2 | |
| SCHEMBL8277418 | 0.70 | PDE3B (0.41) | TRPA1MAOAMAOBCYP1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7705146-B2 | Hepatitis C inhibitor peptide analogs | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-04-27 | — | — | US | disclosed |
| US-7705146-B2 | Hepatitis C inhibitor peptide analogs | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-04-27 | — | — | US | disclosed |