Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | ATM | Q13315 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | BTK | Q06187 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.34 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.33 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.32 |
| ▸ | SYK | P43405 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8135245 | 0.81 | ALDH1A1 (0.48) | MAPTALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL13966259 | 0.78 | ATM (0.56) | MAPTATMTSHRL3MBTL1BTK | |
| SCHEMBL8272972 | 0.75 | PDE4A (0.33) | MAPTTSHRL3MBTL1ALDH1A1KDM4E | |
| SCHEMBL13409366 | 0.72 | TRPA1 (0.39) | TRPM8CYP1A2LRRK2 | |
| SCHEMBL13169635 | 0.72 | GPR3 (0.55) | MAPTTSHRALDH1A1KDM4ECYP1A2 | |
| SCHEMBL13966274 | 0.69 | MAPT (0.48) | MAPTATMTSHRL3MBTL1BTK | |
| SCHEMBL13966263 | 0.69 | ATM (0.45) | MAPTATMTSHRL3MBTL1BTK | |
| SCHEMBL13966260 | 0.69 | HTR4 (0.47) | MAPTATMTSHRL3MBTL1BTK | |
| SCHEMBL13224394 | 0.68 | PDE4A (0.32) | MAPTTSHRL3MBTL1ALDH1A1KDM4E | |
| SCHEMBL1653524 | 0.68 | TDP1 (0.43) | MAPTALDH1A1KDM4EKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7705146-B2 | Hepatitis C inhibitor peptide analogs | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-04-27 | — | — | US | disclosed |
| US-7705146-B2 | Hepatitis C inhibitor peptide analogs | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-04-27 | — | — | US | disclosed |