Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.36 |
| ▸ | ELANE | P08246 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8273081 | 0.84 | MAPT (0.57) | L3MBTL1KMT2AMEN1KDM4EMAPT | |
| SCHEMBL13409393 | 0.84 | MAPT (0.38) | L3MBTL1MAPTALDH1A1LMNAELANE | |
| SCHEMBL13409387 | 0.84 | LMNA (0.35) | KMT2AALDH1A1LMNAELANENPC1 | |
| SCHEMBL13409394 | 0.84 | NR4A2 (0.42) | L3MBTL1KDM4EALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL13409396 | 0.83 | KDM4E (0.43) | L3MBTL1KMT2AMEN1KDM4EMAPT | |
| SCHEMBL13409386 | 0.82 | POLB (0.36) | L3MBTL1KMT2AKDM4EMAPTALDH1A1 | |
| SCHEMBL13409391 | 0.81 | ADORA3 (0.34) | L3MBTL1KMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL8277736 | 0.81 | KDM4E (0.48) | L3MBTL1KMT2AMEN1KDM4EMAPT | |
| SCHEMBL8271698 | 0.81 | KMT2A (0.46) | L3MBTL1KMT2AMEN1KDM4EMAPT | |
| SCHEMBL8142999 | 0.79 | MAPT (0.49) | L3MBTL1KMT2AMEN1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7705146-B2 | Hepatitis C inhibitor peptide analogs | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-04-27 | — | — | US | disclosed |
| US-7705146-B2 | Hepatitis C inhibitor peptide analogs | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-04-27 | — | — | US | disclosed |