Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CDK1 | P06493 | 1/20 | 0.38 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 2/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | HTR1D | P28221 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | HTR3A | P46098 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13409388 | 0.84 | L3MBTL1 (0.45) | LMNAL3MBTL1ALDH1A1PARP1HTR1A | |
| SCHEMBL13409393 | 0.83 | MAPT (0.38) | LMNAL3MBTL1ALDH1A1MAPK8NPC1 | |
| SCHEMBL13409387 | 0.83 | LMNA (0.35) | LMNAALDH1A1HTR1AHTR2CHTR7 | |
| SCHEMBL8273087 | 0.82 | NR4A2 (0.45) | NR4A2LMNACDK1CCNB1L3MBTL1 | |
| SCHEMBL13763738 | 0.82 | ALDH1A1 (0.43) | NR4A2LMNACDK1CCNB1L3MBTL1 | |
| SCHEMBL13385166 | 0.82 | NR4A2 (0.42) | NR4A2L3MBTL1NR1H4ALDH1A1POLB | |
| SCHEMBL13409396 | 0.82 | KDM4E (0.43) | LMNAL3MBTL1ALDH1A1POLBHTR1A | |
| SCHEMBL1021189 | 0.81 | NR4A2 (0.41) | NR4A2LMNACDK1CCNB1L3MBTL1 | |
| SCHEMBL13409386 | 0.81 | POLB (0.36) | LMNAL3MBTL1ALDH1A1POLBMAPK8 | |
| SCHEMBL8131306 | 0.80 | CRHR1 (0.43) | NR4A2LMNAL3MBTL1ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7705146-B2 | Hepatitis C inhibitor peptide analogs | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-04-27 | — | — | US | disclosed |