Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | GABRP | O00591 | 1/20 | 0.34 |
| ▸ | GABRD | O14764 | 1/20 | 0.34 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.34 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.34 |
| ▸ | GABRE | P78334 | 1/20 | 0.34 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13409388 | 0.84 | L3MBTL1 (0.45) | MAPTSMN1; SMN2ALDH1A1LMNAGABRA1 | |
| SCHEMBL13409387 | 0.83 | LMNA (0.35) | ALDH1A1LMNAGABRA1GABRG2GABRB3 | |
| SCHEMBL13409394 | 0.83 | NR4A2 (0.42) | SMN1; SMN2ALDH1A1LMNANPC1MAPK1 | |
| SCHEMBL13409396 | 0.82 | KDM4E (0.43) | MAPTSMN1; SMN2ALDH1A1LMNANPC1 | |
| SCHEMBL13409386 | 0.81 | POLB (0.36) | MAPTSMN1; SMN2ALDH1A1LMNAGABRA1 | |
| SCHEMBL13409391 | 0.80 | ADORA3 (0.34) | SMN1; SMN2ALDH1A1LMNAGABRA1GABRG2 | |
| SCHEMBL13409395 | 0.78 | BCL2L1 (0.36) | MAPTSMN1; SMN2ALDH1A1LMNAADORA2A | |
| SCHEMBL13409389 | 0.76 | MAPT (0.36) | MAPTSMN1; SMN2ALDH1A1LMNAMAPK1 | |
| SCHEMBL13409390 | 0.74 | SOAT1 (0.34) | SMN1; SMN2ALDH1A1BCL2L1BCL2MCL1 | |
| SCHEMBL13409406 | 0.73 | MEN1 (0.38) | MAPTSMN1; SMN2ALDH1A1LMNANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7705146-B2 | Hepatitis C inhibitor peptide analogs | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-04-27 | — | — | US | disclosed |