Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 3/20 | 0.36 |
| ▸ | MMP2 | P08253 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.35 |
| ▸ | ITGAV | P06756 | 1/20 | 0.35 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL3684585 | 0.93 | ITGB3 (0.38) | SMN1; SMN2HTTLMNAMAPTALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL3684591 | 0.93 | ITGB3 (0.38) | SMN1; SMN2HTTLMNAMAPTALDH1A1 | |
| SCHEMBL13409995 | 0.92 | ALDH1A1 (0.39) | SMN1; SMN2HTTLMNAMAPTALDH1A1 | |
| SCHEMBL13410002 | 0.89 | S1PR1 (0.42) | ALDH1A1MMP9MMP2 | |
| SCHEMBL14823024 | 0.88 | NR3C1 (0.40) | SMN1; SMN2HTTLMNAMAPTALDH1A1 | |
| SCHEMBL13409991 | 0.88 | AKR1C3 (0.39) | SMN1; SMN2HTTLMNAMAPTALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL3689890 | 0.84 | EEF2K (0.35) | SMN1; SMN2HTTLMNAMAPTALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL3689887 | 0.84 | EEF2K (0.35) | SMN1; SMN2HTTLMNAMAPTALDH1A1 | |
| SCHEMBL3684588 | 0.84 | HTT (0.33) | SMN1; SMN2HTTLMNAMAPTALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL3682804 | 0.83 | MMP2 (0.40) | MMP9MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8410150-B2 | Inhibitors of carnitine palmitoyltransferase and treating cancer | UNIVERSITY HEALTH NETWORK (CA) | 2013-04-02 | — | — | US | disclosed |
| US-20100105900-A1 | INHIBITORS OF CARNITINE PALMITOYLTRANSFERASE AND TREATING CANCER | UNIVERSITY HEALTH NETWORK | 2010-04-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100105900-A1 | INHIBITORS OF CARNITINE PALMITOYLTRANSFERASE AND TREATING CANCER | CPT1A, CPT1B, CPT2 | SMN1; SMN2 1205/4885HTT 1592/4885LMNA 2918/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.