Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.44 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.44 |
| ▸ | P2RX2 | Q9UBL9 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | GAPDH | P04406 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HRAS | P01112 | 1/20 | 0.43 |
| ▸ | DOT1L | Q8TEK3 | 2/20 | 0.38 |
| ▸ | RNMT | O43148 | 1/20 | 0.38 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.38 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.38 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.38 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.38 |
| ▸ | ADK | P55263 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13410394 | 0.89 | MEN1 (0.46) | MEN1USP2POLBKMT2AP2RX3 | |
| SCHEMBL7110607 | 0.88 | P2RX3 (0.53) | MEN1USP2POLBKMT2AP2RX3 | |
| SCHEMBL18438874 | 0.81 | HRAS (0.48) | MEN1USP2POLBKMT2AP2RX3 | |
| SCHEMBL18438843 | 0.81 | HRAS (0.48) | MEN1USP2POLBKMT2AP2RX3 | |
| SCHEMBL18874622 | 0.81 | HRAS (0.48) | MEN1USP2POLBKMT2AP2RX3 | |
| SCHEMBL19322725 | 0.80 | HRAS (0.52) | MEN1USP2POLBKMT2AP2RX3 | |
| SCHEMBL18483492 | 0.80 | HRAS (0.52) | MEN1USP2POLBKMT2AP2RX3 | |
| SCHEMBL20938335 | 0.79 | P2RX3 (0.55) | MEN1USP2POLBKMT2AP2RX3 | |
| SCHEMBL1738482 | 0.78 | ADK (0.49) | P2RX3P2RX4P2RX2LMNADOT1L | |
| SCHEMBL6735241 | 0.78 | ADK (0.49) | P2RX3P2RX4P2RX2LMNADOT1L |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100093609-A1 | PRODRUGS OF TRICIRIBINE AND TRICIRIBINE PHOSPHATE | TSRL, INC. | 2010-04-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100093609-A1 | PRODRUGS OF TRICIRIBINE AND TRICIRIBINE PHOSPHATE | TYMP, SLC1A5, TYMS | MEN1 4476/4885USP2 4242/4885POLB 263/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.