Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 3/20 | 0.53 |
| ▸ | P2RX4 | Q99571 | 3/20 | 0.53 |
| ▸ | P2RX2 | Q9UBL9 | 3/20 | 0.53 |
| ▸ | DOT1L | Q8TEK3 | 3/20 | 0.49 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.49 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.49 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.49 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ADK | P55263 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | GAPDH | P04406 | 2/20 | 0.44 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.44 |
| ▸ | HRAS | P01112 | 1/20 | 0.44 |
| ▸ | RNMT | O43148 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20938335 | 0.89 | P2RX3 (0.55) | P2RX3P2RX4P2RX2DOT1LPRMT5 | |
| SCHEMBL20938425 | 0.88 | P2RX3 (0.54) | P2RX3P2RX4P2RX2MEN1USP2 | |
| SCHEMBL1738482 | 0.88 | ADK (0.49) | P2RX3P2RX4P2RX2DOT1LPRMT5 | |
| SCHEMBL13410451 | 0.88 | MEN1 (0.45) | P2RX3P2RX4P2RX2DOT1LPRMT5 | |
| SCHEMBL6735241 | 0.88 | ADK (0.49) | P2RX3P2RX4P2RX2DOT1LPRMT5 | |
| SCHEMBL18438843 | 0.87 | HRAS (0.48) | P2RX3P2RX4P2RX2DOT1LPRMT5 | |
| SCHEMBL18438874 | 0.87 | HRAS (0.48) | P2RX3P2RX4P2RX2DOT1LPRMT5 | |
| SCHEMBL18874622 | 0.87 | HRAS (0.48) | P2RX3P2RX4P2RX2DOT1LPRMT5 | |
| SCHEMBL6099599 | 0.85 | P2RX3 (0.55) | P2RX3P2RX4P2RX2MEN1USP2 | |
| SCHEMBL6099608 | 0.85 | P2RX3 (0.55) | P2RX3P2RX4P2RX2MEN1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003061576-A2 | DEAZAPURINE NUCLEOSIDE ANALOGS AND THEIR USE AS THERAPEUTIC AGENTS | RIBAPHARM INC. (US) | 2003-07-31 | — | — | WO | disclosed |