Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPL | P05186 | 3/20 | 0.36 |
| ▸ | ALPI | P09923 | 3/20 | 0.36 |
| ▸ | ALPG | P10696 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 2/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.32 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL132389 | 0.92 | CHEK1 (0.37) | ALPLALPIALPGMEN1KMT2A | |
| SCHEMBL663226 | 0.87 | CHRM3 (0.44) | CHRM3 | |
| SCHEMBL101815 | 0.85 | ALPL (0.37) | ALPLALPIALPGMEN1KMT2A | |
| SCHEMBL175794 | 0.84 | CDK8 (0.42) | MMP2MMP3 | |
| SCHEMBL99659 | 0.82 | POLB (0.40) | MMP2MMP3POLBALDH1A1LMNA | |
| SCHEMBL660644 | 0.82 | NPC1 (0.38) | ALPLALPIALPGMEN1KMT2A | |
| SCHEMBL15822512 | 0.81 | CHEK1 (0.36) | ALPLALPIALPGMEN1KMT2A | |
| SCHEMBL15823424 | 0.81 | CHEK1 (0.35) | CHRM3SMN1; SMN2HPGDBCHEACHE | |
| SCHEMBL15822514 | 0.81 | CHEK1 (0.36) | ALPLALPIALPGMEN1KMT2A | |
| SCHEMBL99550 | 0.80 | MCHR1 (0.40) | HDAC1HDAC2ALDH1A1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2426121-A1 | QUATERNARY AMMONIUM SALT COMPOUND | Teijin Pharma Limited (JP) | 2012-03-07 | — | — | EP | disclosed |