Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | MMP2 | P08253 | 4/20 | 0.38 |
| ▸ | MMP3 | P08254 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | MMP14 | P50281 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL97653 | 0.91 | CHEK1 (0.42) | POLBHPGDRAB9ANPC1LTB4R | |
| SCHEMBL99375 | 0.88 | NPC1 (0.49) | POLBHPGDRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL100027 | 0.87 | GAA (0.39) | POLBRAB9ANPC1SMN1; SMN2LMNA | |
| SCHEMBL663226 | 0.87 | CHRM3 (0.44) | — | |
| SCHEMBL100933 | 0.87 | POLB (0.46) | POLBHPGDMMP2MMP3RAB9A | |
| SCHEMBL99141 | 0.87 | NPC1 (0.48) | POLBHPGDRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL100322 | 0.86 | HPGD (0.44) | POLBHPGDRAB9ANPC1LTB4R | |
| SCHEMBL99071 | 0.84 | RAB9A (0.43) | RAB9ANPC1LTB4RSMN1; SMN2LMNA | |
| SCHEMBL99117 | 0.83 | CHEK1 (0.38) | POLBHPGDRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL134109 | 0.82 | ALPL (0.36) | POLBHPGDMMP2MMP3SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2426121-A1 | QUATERNARY AMMONIUM SALT COMPOUND | Teijin Pharma Limited (JP) | 2012-03-07 | — | — | EP | claimed |