Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.36 |
| ▸ | ALPL | P05186 | 3/20 | 0.36 |
| ▸ | ALPI | P09923 | 3/20 | 0.36 |
| ▸ | ALPG | P10696 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 3/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL134109 | 0.92 | ALPL (0.36) | CHRM3ALPLALPIALPGMEN1 | |
| SCHEMBL15822514 | 0.88 | CHEK1 (0.36) | CHEK1CHRM3ADRB2ALPLALPI | |
| SCHEMBL15823424 | 0.88 | CHEK1 (0.35) | CHEK1CHRM3ADRB2BCHEACHE | |
| SCHEMBL15822512 | 0.88 | CHEK1 (0.36) | CHEK1CHRM3ADRB2ALPLALPI | |
| SCHEMBL132259 | 0.87 | CHRM3 (0.45) | CHEK1CHRM3ADRB2CHRM2 | |
| SCHEMBL101815 | 0.85 | ALPL (0.37) | CHRM3ADRB2ALPLALPIALPG | |
| SCHEMBL663673 | 0.85 | CHRM3 (0.44) | CHRM3ADRB2CHRM2 | |
| SCHEMBL175794 | 0.84 | CDK8 (0.42) | — | |
| SCHEMBL663010 | 0.83 | CHRM3 (0.46) | CHRM3ADRB2CHRM2HPGD | |
| SCHEMBL97653 | 0.82 | CHEK1 (0.42) | CHEK1HPGDPOLBGAAALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2426121-A1 | QUATERNARY AMMONIUM SALT COMPOUND | Teijin Pharma Limited (JP) | 2012-03-07 | — | — | EP | disclosed |
| US-20120046467-A1 | QUATERNARY AMMONIUM SALT COMPOUNDS | TEIJIN PHARMA LIMITED (JP) | 2012-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120046467-A1 | QUATERNARY AMMONIUM SALT COMPOUNDS | ADRB2, AGTR2, ADRB3 | CHEK1 4054/4885CHRM3 9/4885ADRB2 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.