Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13531884 | 0.89 | HPGD (0.45) | TSHRALDH1A1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL13411276 | 0.87 | FAAH (0.47) | TSHRALDH1A1LMNAKDM4ERECQL | |
| SCHEMBL14253421 | 0.83 | TSHR (0.70) | TSHRALDH1A1LMNAKDM4ERECQL | |
| SCHEMBL11928872 | 0.82 | TSHR (0.38) | TSHRALDH1A1LMNAKDM4ERECQL | |
| SCHEMBL15075515 | 0.81 | FAAH (0.56) | TSHRRECQLMEN1KMT2AFAAH | |
| SCHEMBL16182412 | 0.81 | TSHR (0.56) | TSHRALDH1A1RECQLSMN1; SMN2GAA | |
| SCHEMBL13034763 | 0.81 | TSHR (0.43) | TSHRALDH1A1RECQLMEN1KMT2A | |
| SCHEMBL12733561 | 0.81 | CES2 (0.51) | TSHRALDH1A1RECQLSMN1; SMN2HSD17B10 | |
| SCHEMBL12734797 | 0.81 | TSHR (0.41) | TSHRALDH1A1KDM4EHPGDMEN1 | |
| SCHEMBL29330747 | 0.81 | TSHR (0.41) | TSHRALDH1A1KDM4EHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100056543-A1 | POSACONAZOLE POLYMER CONJUGATES AND METHODS OF TREATMENT USING POSACONAZOLE AND POLYMER CONJUGATES THEREOF | ENZON PHARMACEUTICALS, INC. (US) | 2010-03-04 | — | — | US | disclosed |
| US-7625898-B2 | Posaconazole polymer conjugates and methods of treatment using posaconazole and polymer conjugates thereof | ENZON PHARMACEUTICALS, INC. (US) | 2009-12-01 | — | — | US | disclosed |
| US-20080171013-A1 | POSACONAZOLE POLYMER CONJUGATES AND METHODS OF TREATMENT USING POSACONAZOLE AND POLYMER CONJUGATES THEREOF | ENZON PHARMACEUTICALS, INC. (US) | 2008-07-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080171013-A1 | POSACONAZOLE POLYMER CONJUGATES AND METHODS OF TREATMENT USING POSACONAZOLE AND POLYMER CONJUGATES THEREOF | ALG1, DDOST, B3GAT3 | TSHR 3167/4885ALDH1A1 2736/4885LMNA 3880/4885 |
| US-20100056543-A1 | POSACONAZOLE POLYMER CONJUGATES AND METHODS OF TREATMENT USING POSACONAZOLE AND POLYMER CONJUGATES THEREOF | ALG1, DDOST, B3GAT3 | TSHR 3167/4885ALDH1A1 2736/4885LMNA 3880/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.