Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | IDO1 | P14902 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | MB | P02144 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7978815 | 0.95 | LMNA (0.58) | LMNAMEN1KMT2APOLBIDO1 | |
| SCHEMBL3071609 | 0.87 | LMNA (0.71) | LMNAMEN1KMT2APOLBL3MBTL1 | |
| SCHEMBL14992464 | 0.87 | KMT2A (0.59) | LMNAMEN1KMT2APOLBIDO1 | |
| SCHEMBL23412709 | 0.86 | LMNA (0.48) | LMNAMEN1KMT2APOLBIDO1 | |
| SCHEMBL707356 | 0.86 | LMNA (0.48) | LMNAMEN1KMT2APOLBIDO1 | |
| SCHEMBL2729176 | 0.86 | GRM4 (0.51) | LMNAMEN1KMT2APOLBIDO1 | |
| SCHEMBL21855109 | 0.84 | L3MBTL1 (0.53) | LMNAMEN1KMT2APOLBIDO1 | |
| SCHEMBL21282782 | 0.82 | GAA (0.51) | LMNAMEN1KMT2APOLBIDO1 | |
| SCHEMBL17896331 | 0.82 | ALDH1A1 (0.51) | LMNAMEN1KMT2APOLBIDO1 | |
| SCHEMBL23442130 | 0.82 | IDO1 (0.47) | LMNAMEN1KMT2APOLBIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8466180-B2 | Insecticidal compounds | SYNGENTA CROP PROTECTION LLC (US) | 2013-06-18 | — | — | US | disclosed |
| US-20100076078-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CORP PROTECTION, INC. (US) | 2010-03-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100076078-A1 | INSECTICIDAL COMPOUNDS | ACHE, CHRM1, CHRM2 | LMNA 1133/4885MEN1 1427/4885KMT2A 2280/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.