Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TRIM24 | O15164 | 2/20 | 0.32 |
| ▸ | TRIM33 | Q9UPN9 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31267818 | 0.86 | — | — | |
| SCHEMBL1803997 | 0.79 | ALDH1A1 (0.37) | TRIM24TRIM33ALDH1A1 | |
| SCHEMBL13414708 | 0.75 | CYP1A2 (0.31) | — | |
| SCHEMBL1802879 | 0.75 | GAA (0.33) | — | |
| SCHEMBL14831580 | 0.74 | — | — | |
| SCHEMBL2556088 | 0.72 | — | — | |
| SCHEMBL1803215 | 0.70 | GAA (0.35) | ALDH1A1 | |
| SCHEMBL31267848 | 0.70 | SMN1; SMN2 (0.41) | ALDH1A1 | |
| SCHEMBL10587818 | 0.70 | CRBN (0.33) | CRBN | |
| SCHEMBL2040617 | 0.68 | CYP11B1 (0.38) | MEN1CYP2C9KMT2ATRIM24TRIM33 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8513417-B2 | Method for synthesis of nitroxyl radical | KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) | 2013-08-20 | — | — | US | disclosed |
| US-8513417-B2 | Method for synthesis of nitroxyl radical | KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) | 2013-08-20 | — | — | US | disclosed |
| US-20100076190-A1 | METHOD FOR SYNTHESIS OF NITROXYL RADICAL | KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) | 2010-03-25 | — | — | US | disclosed |
| US-20100076190-A1 | METHOD FOR SYNTHESIS OF NITROXYL RADICAL | KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) | 2010-03-25 | — | — | US | disclosed |
| EP-2128135-A1 | METHOD FOR SYNTHESIS OF NITROXYL RADICAL | Kyushu University, National University Corporation (JP) | 2009-12-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100076190-A1 | METHOD FOR SYNTHESIS OF NITROXYL RADICAL | NOX4, TXN2, TXNRD2 | MEN1 3504/4885CYP2C9 1164/4885KMT2A 665/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.