SCHEMBL134151

SCHEMBL134151

C/C=C/CC(C)C(=O)OC

nearest known ligand 0.39

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CTSK P43235 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.37
GRIK1 P39086 2/20 0.36
GRIK2 Q13002 2/20 0.36
TSHR P16473 3/20 0.35
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
CA14 Q9ULX7 2/20 0.34
PPARG P37231 1/20 0.33
PPARD Q03181 1/20 0.33
PPARA Q07869 1/20 0.33
CA12 O43570 1/20 0.32
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
ESRRB O95718 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL132110 1.00 CTSK (0.39) CTSKSMN1; SMN2GRIK1GRIK2TSHR
SCHEMBL13706426 0.83 SMN1; SMN2 (0.37) SMN1; SMN2TSHRMEN1KMT2ACA14
SCHEMBL7668341 0.82
SCHEMBL3866367 0.81 ALDH1A1 (0.37) CTSKGRIK1GRIK2
SCHEMBL11865860 0.80 CTSK (0.40) CTSKSMN1; SMN2GRIK1GRIK2TSHR
SCHEMBL11865851 0.80 CTSK (0.40) CTSKSMN1; SMN2GRIK1GRIK2TSHR
SCHEMBL28363798 0.79 PPARG (0.38) SMN1; SMN2TSHRMEN1KMT2ACA14
SCHEMBL9653054 0.78 CTSK (0.36) CTSKSMN1; SMN2GRIK1GRIK2TSHR
Hydrochloric Acid SCHEMBL29046668 0.78 PPARG (0.37) SMN1; SMN2TSHRMEN1KMT2ACA14
SCHEMBL16866044 0.78 SMN1; SMN2 (0.33) SMN1; SMN2GRIK1GRIK2TSHRMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4219008-B1 USE FOR THE TREATMENT OF AN ION EXCHANGE RESIN MITSUBISHI CHEMICAL UK LTD (GB) 2024-11-20 EP disclosed
EP-4049754-B1 PROCESS FOR THE TREATMENT OF AN ION EXCHANGE RESIN MITSUBISHI CHEMICAL UK LTD (GB) 2024-04-03 EP disclosed
EP-4219008-A1 USE FOR THE TREATMENT OF AN ION EXCHANGE RESIN Mitsubishi Chemical UK Limited (GB) 2023-08-02 EP disclosed
EP-3862085-B1 PROCESS FOR THE TREATMENT OF AN ION EXCHANGE RESIN MITSUBISHI CHEMICAL UK LTD (GB) 2023-06-07 EP disclosed
EP-4049754-A1 PROCESS FOR THE TREATMENT OF AN ION EXCHANGE RESIN Mitsubishi Chemical UK Limited (GB) 2022-08-31 EP disclosed
EP-2411147-B1 PROCESS FOR THE TREATMENT OF AN ION EXCHANGE RESIN MITSUBISHI CHEMICAL UK LTD (GB) 2022-04-20 EP disclosed
EP-3862085-A1 PROCESS FOR THE TREATMENT OF AN ION EXCHANGE RESIN Mitsubishi Chemical UK Limited (GB) 2021-08-11 EP disclosed
US-9821304-B2 Process for the treatment of an ion exchange resin LUCITE INTERNATIONAL UK LIMITED (GB) 2017-11-21 US disclosed
US-20140343176-A1 PROCESS FOR THE TREATMENT OF AN ION EXCHANGE RESIN Mitsubishi Chemical UK Limited (GB) 2014-11-20 US disclosed
US-8835518-B2 Process for the treatment of an ion exchange resin LUCITE INTERNATIONAL UK LIMITED (GB) 2014-09-16 US disclosed
US-20120059073-A1 PROCESS FOR THE TREATMENT OF AN ION EXCHANGE RESIN LUCITE INTERNATIONAL UK LIMITED (GB) 2012-03-08 US disclosed
EP-2411147-A2 PROCESS FOR THE TREATMENT OF AN ION EXCHANGE RESIN Lucite International UK Limited (GB) 2012-02-01 EP disclosed
WO-2010109244-A2 PROCESS FOR THE TREATMENT OF AN ION EXCHANGE RESIN LUCITE INTERNATIONAL UK LIMITED (GB) 2010-09-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120059073-A1 PROCESS FOR THE TREATMENT OF AN ION EXCHANGE RESIN RCOR1, RER1, DECR1 CTSK 4458/4885SMN1; SMN2 2107/4885GRIK1 2879/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.