Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 8/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 5/20 | 0.50 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.50 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13416485 | 0.81 | SIGMAR1 (0.63) | SIGMAR1TAAR1SLC18A2TRPA1SLC6A2 | |
| SCHEMBL13416383 | 0.81 | SIGMAR1 (0.63) | SIGMAR1TAAR1SLC18A2TRPA1SLC6A2 | |
| SCHEMBL19290098 | 0.80 | SIGMAR1 (0.46) | SIGMAR1TAAR1SLC18A2SLC6A2MAOA | |
| SCHEMBL5072576 | 0.78 | SIGMAR1 (0.68) | SIGMAR1TAAR1SLC18A2SLC6A4CYP2D6 | |
| SCHEMBL5072573 | 0.78 | SIGMAR1 (0.68) | SIGMAR1TAAR1SLC18A2SLC6A4CYP2D6 | |
| SCHEMBL23894006 | 0.78 | TRPA1 (0.42) | SIGMAR1TAAR1SLC18A2TRPA1SLC6A2 | |
| Hydrochloric Acid SCHEMBL7037528 | 0.77 | SIGMAR1 (0.66) | SIGMAR1TAAR1SLC18A2SLC6A4CYP2D6 | |
| Hydrochloric Acid SCHEMBL7037524 | 0.77 | SIGMAR1 (0.66) | SIGMAR1TAAR1SLC18A2SLC6A4CYP2D6 | |
| SCHEMBL19565108 | 0.76 | SIGMAR1 (0.47) | SIGMAR1TAAR1SLC18A2TRPA1SLC6A2 | |
| SCHEMBL13884126 | 0.76 | SIGMAR1 (0.47) | SIGMAR1TAAR1SLC18A2TRPA1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100076015-A1 | Aminopyridine Derivatives | VANTIA LIMITED (GB) | 2010-03-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100076015-A1 | Aminopyridine Derivatives | CHRM1, ARG1, ARG2 | SIGMAR1 1154/4885TAAR1 661/4885SLC18A2 2378/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.