SCHEMBL134170

SCHEMBL134170

COC(=O)c1cccc(N)c1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LOXL2 Q9Y4K0 1/20 0.61
TSHR P16473 1/20 0.57
ALDH1A1 P00352 3/20 0.56
PBRM1 Q86U86 1/20 0.55
KDM4E B2RXH2 2/20 0.55
GAA P10253 2/20 0.55
GLA P06280 1/20 0.55
MAPT P10636 1/20 0.55
HPGD P15428 1/20 0.55
CASP1 P29466 1/20 0.55
CASP7 P55210 1/20 0.55
ATM Q13315 1/20 0.55
HSD17B10 Q99714 1/20 0.55
CYP4F2 P78329 2/20 0.54
CYP4A11 Q02928 2/20 0.54
POLB P06746 2/20 0.53
RAB9A P51151 2/20 0.53
ADRB2 P07550 2/20 0.52
ADRB1 P08588 2/20 0.52
ADRB3 P13945 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29836775 1.00 LOXL2 (0.61) LOXL2TSHRALDH1A1PBRM1KDM4E
Hydrochloric Acid SCHEMBL2477797 0.98 LOXL2 (0.59) LOXL2TSHRALDH1A1PBRM1KDM4E
O-Xylene SCHEMBL27792225 0.91 LMNA (0.57) LOXL2TSHRALDH1A1PBRM1KDM4E
Toluene SCHEMBL27792204 0.90 TSHR (0.56) LOXL2TSHRALDH1A1PBRM1KDM4E
SCHEMBL29441704 0.89 CA12 (0.61) LOXL2TSHRALDH1A1MAPTRAB9A
SCHEMBL2875365 0.89 CA12 (0.61) LOXL2TSHRALDH1A1MAPTRAB9A
SCHEMBL7531618 0.88 LOXL2 (0.50) LOXL2TSHRALDH1A1PBRM1KDM4E
Hydrochloric Acid SCHEMBL6233341 0.88 CA12 (0.60) LOXL2TSHRALDH1A1MAPTRAB9A
SCHEMBL7908137 0.88 PBRM1 (0.66) LOXL2TSHRALDH1A1PBRM1KDM4E
SCHEMBL8367495 0.86 L3MBTL1 (0.56) LOXL2TSHRALDH1A1HPGDRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2941 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3967714-B1 VINYL ALCOHOL-AMINO ACID ESTER COPOLYMER, THEIR PREPARATION AND USES SEKISUI CHEMICAL CO LTD (JP) 2026-01-07 EP claimed
CN-119930494-A Aryl compound, preparation method thereof and application thereof in preparation of anti-inflammatory and anti-tumor drugs 首都医科大学 2025-05-06 CN claimed
CN-119874681-A Indole derivative, preparation method thereof and application of indole derivative in resisting liver cancer 中国人民解放军北部战区总医院 2025-04-25 CN claimed
CN-115466341-B Ashless dispersant and preparation method thereof 新乡市瑞丰新材料股份有限公司 2024-12-20 CN claimed
EP-4452952-A1 A PREPARATION OF QUINAZOLINEDIONES AND USE THEREOF Council of Scientific and Industrial Research, an Indian Registered Body Incorporated under Regn. of Soc. Act (Act XXI of 1860) (IN) 2024-10-30 EP claimed
CN-118546466-B Modified polypropylene material and preparation method thereof 佛山市维卡塑料科技有限公司 2024-10-29 CN claimed
CN-118619922-A Hydroxamic acid compound, and preparation method and application thereof 郑州大学 2024-09-10 CN claimed
CN-118546466-A Modified polypropylene material and preparation method thereof 佛山市维卡塑料科技有限公司 2024-08-27 CN claimed
CN-118451062-A Preparation and use of quinazolinediones 科学与工业研究会(按照印度社会团体注册法案(1860年第21号法案)设立的注册机构) 2024-08-06 CN claimed
CN-116354901-A Thiazolidinedione compound and preparation method and application thereof 郑州大学 2023-06-30 CN claimed
CN-101910193-A Semi-recombinant preparation method of GLP-1 analogue NOVO NORDISK AS 2010-12-08 CN claimed
US-20100075962-A1 INDOL DERIVATIVES, THE METHOD FOR PREPARING THEREOF AND COMPOSITION FOR THE PREVENTION AND TREATMENT OF METABOLIC DISORDER CONTAINING THE SAME AS AN ACTIVE INGREDIENT KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) 2010-03-25 US claimed
CN-101631566-A Polar hydrophilic prodrugs of amphetamine and other stimulants and processes for making and using the same KEMPHARM INC 2010-01-20 CN claimed
WO-2008039007-A1 INDOL DERIVATIVES, THE METHOD FOR PREPARING THEREOF AND COMPOSITION FOR THE PREVENTION AND TREATMENT OF METABOLIC DISORDER CONTAINING THE SAME AS AN ACTIVE INGREDIENT KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) 2008-04-03 WO claimed
EP-1163262-A1 PHENYLALANINE DERIVATIVES THE GOVERNMENT OF THE UNITED STATES OF AMERICA as represented by THE SECRETARY of the DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2001-12-19 EP claimed
WO-2000056760-A1 PHENYLALANINE DERIVATIVES THE UNITED STATES OF AMERICA, REPRESENTED BY SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2000-09-28 WO claimed
EP-1004654-A2 Adjuvants and methods for raising intracellular calcium ion concentration Takasago International Corporation (JP) 2000-05-31 EP claimed
CN-1052731-C Compounds with growth hormone releasing properties NOVO NORDISK AS (DK) 2000-05-24 CN claimed
US-5391699-A Containing an aromatic amine carboxylate, heat resistance BRIDGESTONE CORPORATION (JP) 1995-02-21 US claimed
EP-0571095-A2 Polyester copolymer and process for the production of the same BRIDGESTONE CORPORATION (JP) 1993-11-24 EP claimed