Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | MMP3 | P08254 | 1/20 | 0.45 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
| ▸ | BAX | Q07812 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL562844 | 0.82 | KMT2A (0.41) | LTA4HMEN1KMT2A | |
| SCHEMBL17082320 | 0.80 | LMNA (0.49) | LMNACYP1A2PTGS1SLC6A2CYP2C19 | |
| SCHEMBL12646235 | 0.79 | MMP3 (0.52) | LMNACYP1A2PTGS1SLC6A2CYP2C19 | |
| SCHEMBL28901704 | 0.76 | MMP3 (0.48) | LMNACYP1A2PTGS1SLC6A2CYP2C19 | |
| SCHEMBL27966252 | 0.74 | ESR2 (0.52) | LMNAMMP3BCL2L1LTA4HNR1H2 | |
| SCHEMBL23777847 | 0.73 | LTA4H (0.48) | LMNACYP1A2PTGS1SLC6A2CYP2C19 | |
| SCHEMBL254671 | 0.73 | LMNA (0.88) | LMNACYP1A2PTGS1SLC6A2CYP2C19 | |
| SCHEMBL10295109 | 0.72 | LTA4H (0.58) | LMNACYP1A2PTGS1SLC6A2CYP2C19 | |
| SCHEMBL6059234 | 0.72 | LMNA (0.85) | LMNACYP1A2PTGS1SLC6A2CYP2C19 | |
| Sulfur Dioxide SCHEMBL28532111 | 0.71 | LMNA (0.76) | LMNACYP1A2PTGS1SLC6A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8642165-B2 | Organic-inorganic hybrid composition | FUJIFILM CORPORATION (JP) | 2014-02-04 | — | — | US | disclosed |
| US-20100104842-A1 | ORGANIC-INORGANIC HYBRID COMPOSITION | FUJIFILM CORPORATION (JP) | 2010-04-29 | — | — | US | disclosed |