Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | BAD | Q92934 | 1/20 | 0.44 |
| ▸ | CDC25B | P30305 | 1/20 | 0.41 |
| ▸ | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 | P62805 | 1/20 | 0.41 |
| ▸ | EP300 | Q09472 | 1/20 | 0.41 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 9/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.39 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14096678 | 0.89 | BCL2L1 (0.42) | BCL2MCL1BADCDC25BH4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 | |
| SCHEMBL13423240 | 0.84 | PDK2 (0.50) | PDK2TDP1L3MBTL1 | |
| SCHEMBL13423255 | 0.84 | PDK2 (0.43) | CDC25BPDK2MEN1KMT2AMAPT | |
| SCHEMBL13423248 | 0.84 | PDK2 (0.43) | CDC25BPDK2MEN1KMT2AMAPT | |
| SCHEMBL13423247 | 0.84 | PDK2 (0.43) | PDK2MEN1KMT2AMAPTTDP1 | |
| SCHEMBL13423239 | 0.81 | PDK2 (0.48) | PDK2TDP1L3MBTL1 | |
| SCHEMBL13423252 | 0.81 | PDK2 (0.58) | CNR2PDK2MEN1KMT2ATDP1 | |
| SCHEMBL13423232 | 0.81 | PDK2 (0.58) | CNR2PDK2MEN1KMT2ATDP1 | |
| SCHEMBL13423257 | 0.81 | PDK2 (0.58) | CNR2PDK2MEN1KMT2ATDP1 | |
| SCHEMBL13781074 | 0.81 | BCL2 (0.41) | BCL2MCL1BADCDC25BH4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7683229-B2 | truxene and isotruxene derivatives, in particular spirotruxene and spiroisotruxene derivatives; use thereof in organic electronic devices, in particular organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2010-03-23 | — | — | US | disclosed |
| US-20080093980-A1 | Organic Electroluminescent Device | MERCK PATENT GMBH (DE) | 2008-04-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080093980-A1 | Organic Electroluminescent Device | OXER1, NR3C2, OXTR | BCL2 1953/4885MCL1 4560/4885BAD 1057/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.