Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 6/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.46 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13425461 | 0.89 | MEN1 (0.53) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL4681912 | 0.85 | NPBWR1 (0.48) | NPC1RAB9AMAPTSMN1; SMN2HDAC3 | |
| SCHEMBL14290243 | 0.85 | GCGR (0.49) | MAPTSMN1; SMN2HDAC1 | |
| SCHEMBL22613601 | 0.81 | MAPT (0.44) | MEN1KMT2AMAPTSMN1; SMN2HDAC1 | |
| SCHEMBL20600076 | 0.79 | MAPK14 (0.46) | MAPTSMN1; SMN2KDM4ECYP1A2CYP3A4 | |
| SCHEMBL13425922 | 0.78 | MAPT (0.69) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL22613626 | 0.78 | PTGDR (0.48) | MEN1KMT2AMAPTSMN1; SMN2MCHR1 | |
| SCHEMBL20600263 | 0.78 | NPC1 (0.46) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL13426461 | 0.77 | HPGD (0.56) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL14445949 | 0.75 | GCGR (0.51) | MAPTSMN1; SMN2HDAC1LMNACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |