Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 10/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ASIC1 | P78348 | 2/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | GIPR | P48546 | 1/20 | 0.42 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14445949 | 0.90 | GCGR (0.51) | GCGRMAPTSMN1; SMN2ASIC1HDAC1 | |
| SCHEMBL4681912 | 0.88 | NPBWR1 (0.48) | MAPTSMN1; SMN2ASIC1HDAC1 | |
| SCHEMBL4679240 | 0.88 | GCGR (0.51) | GCGRMAPTSMN1; SMN2HDAC1GIPR | |
| SCHEMBL13425858 | 0.85 | MEN1 (0.54) | MAPTSMN1; SMN2HDAC1 | |
| SCHEMBL23297371 | 0.82 | MAPT (0.67) | GCGRMAPTSMN1; SMN2HDAC1HTR2C | |
| SCHEMBL14290130 | 0.80 | GCGR (0.50) | GCGRMAPTSMN1; SMN2HDAC1 | |
| SCHEMBL5418558 | 0.79 | MAPT (0.40) | GCGRMAPTGIPR | |
| SCHEMBL508983 | 0.79 | MAPT (0.45) | GCGRMAPT | |
| SCHEMBL14445943 | 0.79 | GCGR (0.39) | GCGRMAPTHDAC1 | |
| SCHEMBL4683641 | 0.78 | NPBWR1 (0.47) | MAPTSMN1; SMN2ASIC1HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1513796-B1 | PHENYLOXYALKANOIC ACID DERIVATIVES AS HPPAR ACTIVATORS | SMITHKLINE BEECHAM CORP (US) | 2008-02-13 | — | — | EP | disclosed |
| US-7241793-B2 | Phenyloxyalkanonic acid derivatives as hPPAR activators | SMITHKLINE BEECHAM CORPORATION (US) | 2007-07-10 | — | — | US | disclosed |
| US-7241793-B2 | Phenyloxyalkanonic acid derivatives as hPPAR activators | SMITHKLINE BEECHAM CORPORATION (US) | 2007-07-10 | — | — | US | disclosed |