Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPBWR1 | P48145 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.48 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | ASIC1 | P78348 | 2/20 | 0.45 |
| ▸ | ACP1 | P24666 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | TEK | Q02763 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4683641 | 0.90 | NPBWR1 (0.47) | NPBWR1HSP90AA1HSP90AB1MAPTSMN1; SMN2 | |
| SCHEMBL14290243 | 0.88 | GCGR (0.49) | MAPTSMN1; SMN2ASIC1HDAC1 | |
| SCHEMBL13425858 | 0.85 | MEN1 (0.54) | NPBWR1MAPTSMN1; SMN2TP53KDM4E | |
| SCHEMBL4684515 | 0.84 | MEN1 (0.50) | MAPTSMN1; SMN2GRIN1GRIN2BTDP1 | |
| SCHEMBL14445949 | 0.78 | GCGR (0.51) | MAPTSMN1; SMN2ASIC1HDAC1 | |
| SCHEMBL4679427 | 0.78 | TLR8 (0.41) | TEKKDM4EALDH1A1HDAC3HDAC4 | |
| SCHEMBL22613601 | 0.78 | MAPT (0.44) | NPBWR1MAPTSMN1; SMN2TP53KDR | |
| SCHEMBL4682039 | 0.78 | MAPT (0.76) | NPBWR1HSP90AA1MAPTSMN1; SMN2ASIC1 | |
| SCHEMBL14290129 | 0.78 | MAPT (0.58) | NPBWR1HSP90AA1HSP90AB1MAPTSMN1; SMN2 | |
| SCHEMBL4679240 | 0.76 | GCGR (0.51) | MAPTSMN1; SMN2ALDH1A1TDP1HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1513796-B1 | PHENYLOXYALKANOIC ACID DERIVATIVES AS HPPAR ACTIVATORS | SMITHKLINE BEECHAM CORP (US) | 2008-02-13 | — | — | EP | disclosed |
| US-7241793-B2 | Phenyloxyalkanonic acid derivatives as hPPAR activators | SMITHKLINE BEECHAM CORPORATION (US) | 2007-07-10 | — | — | US | disclosed |
| EP-1513796-A2 | PHENYLOXYALKANOIC ACID DERIVATIVES AS HPPAR ACTIVATORS | SMITHKLINE BEECHAM CORPORATION (US) | 2005-03-16 | — | — | EP | disclosed |
| WO-2004000785-A2 | PHENYLOXYALKANONIC ACID DERIVATIVES AS HPPAR ACTIVATORS | SMITHKLINE BEECHAM CORPORATION (US) | 2003-12-31 | — | — | WO | disclosed |