Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA4 | P48058 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8850555 | 0.85 | GABRA1 (0.36) | — | |
| SCHEMBL19427991 | 0.73 | RORC (0.40) | GRIA4TSHRALDH1A1CYP2C9RORC | |
| SCHEMBL18431363 | 0.73 | RORC (0.40) | GRIA4TSHRALDH1A1CYP2C9RORC | |
| SCHEMBL14671240 | 0.72 | NPC1 (0.43) | GRIA4TSHRALDH1A1CYP2C9RORC | |
| SCHEMBL18400912 | 0.72 | ALDH1A1 (0.40) | GRIA4TSHRALDH1A1CYP2C9RORC | |
| SCHEMBL18403080 | 0.72 | RORC (0.42) | GRIA4TSHRALDH1A1CYP2C9RORC | |
| SCHEMBL9220144 | 0.72 | TSHR (0.34) | TSHRNPSR1 | |
| SCHEMBL548052 | 0.72 | GRIA4 (0.53) | GRIA4TSHRALDH1A1CYP2C9RORC | |
| SCHEMBL18092983 | 0.72 | GRIA4 (0.53) | GRIA4TSHRALDH1A1CYP2C9RORC | |
| SCHEMBL4090896 | 0.71 | GABRA1 (0.36) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2172470-A1 | BIPYRIDINE COMPOUND, TRANSITION METAL COMPLEX, AND METHOD FOR PRODUCTION OF CONJUGATED AROMATIC COMPOUND USING THE TRANSITION METAL COMPLEX | Sumitomo Chemical Company, Limited (JP) | 2010-04-07 | — | — | EP | disclosed |